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Developmental basis of disease: environmental impacts

Published online by Cambridge University Press:  23 February 2011

G. W. Collman
G. W. Collman*
Affiliation:
Division of Extramural Research and Training, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
*
*Address for correspondence: Dr G. W. Collman, Division of Extramural Research and Training, National Institute of Environmental Health Sciences, Gwen, PO Box 12233, Research Triangle Park, North Carolina 27709, USA. (Email [email protected])
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Abstract

Exposure to environmental chemicals and other environmental stressors have health impacts on the fetus that may not be apparent until later in life. The concept of developmental origins of disease should be expanded to include these early life exposures in addition to the effects of nutrition and maternal factors. This paper will describe the toxicological, biological and epidemiological issues that are pertinent to conducting research on environmental exposures early in life and their health consequences over the life span.

Keywords

early life exposuresenvironmental chemicalswindows of susceptibility
Type
Themed Content: Role of Environmental Stressors in the Developmental Origins of Disease
Information
Journal of Developmental Origins of Health and Disease , Volume 2 , Issue 1: Including Themed Content: Role of Environmental Stressors in the Developmental Origins of Disease , 23 February 2011 , pp. 49 - 55
Copyright
Copyright © Cambridge University Press and the International Society for Developmental Origins of Health and Disease 2011

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