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Quarter variation and correlations of colostrum albumin, immunoglobulin G1 and G2 in dairy cows

Published online by Cambridge University Press:  06 April 2016

Jaak Samarütel ,
Craig R Baumrucker ,
Josef J Gross ,
Chad D Dechow  and
Rupert M Bruckmaier
Jaak Samarütel
Affiliation:
Veterinary Physiology, Vetsuisse Faculty University of Bern, CH-3012 Bern, Switzerland Estonian University of Life Sciences, Institute of Veterinary Medicine and Animal Science, 51014 Tartu, Estonia
Craig R Baumrucker
Affiliation:
Veterinary Physiology, Vetsuisse Faculty University of Bern, CH-3012 Bern, Switzerland Department of Animal Science, Penn State University, University Park, PA 16802, USA
Josef J Gross
Affiliation:
Veterinary Physiology, Vetsuisse Faculty University of Bern, CH-3012 Bern, Switzerland
Chad D Dechow
Affiliation:
Department of Animal Science, Penn State University, University Park, PA 16802, USA
Rupert M Bruckmaier*
Affiliation:
Veterinary Physiology, Vetsuisse Faculty University of Bern, CH-3012 Bern, Switzerland
*
*For correspondence; e-mail: [email protected]
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Abstract

A high variation in immunoglobulin G1 (IgG1) concentration in first milked quarter colostrum has been reported, but BSA quarter colostrum variation is not known. The occurrence of serum albumin in milk has been attributed to increased blood-milk barrier penetration. Reports of serum albumin binding to the Fc Receptor of the neonate, the receptor thought to be responsible for IgG1 transcytosis, suggested that a correlation with the appearance of IgG1 in colostrum of dairy cows was likely. The objective of the study was to establish the quarter colostrum concentration and mass of immunoglobulins and serum albumin. First colostrum was quarter collected within 4 h of parturition from healthy udders of 31 multiparous dairy cows. Individual quarter colostrum weight was determined and a sample of each was frozen for subsequent analysis. Concentrations of immunoglobulin G1, G2, and BSA were measured by ELISA and total mass of components was calculated. In addition, colostrum was also analysed for L-lactate dehydrogenase activity. Analysis of concentration and mass of BSA, immunoglobulin G1, G2 established that the quarter variations were different by cow, quarter and quarter within cow. Partial correlations corrected for colostrum weight indicated that BSA and IgG2 concentration and mass are closely correlated while that of BSA and IgG1 concentration and mass exhibited no correlation suggesting that BSA and IgG1 may have different transport mechanisms. Interestingly, immunoglobulin G1 and G2 concentration and mass exhibited strong correlations suggesting that also some unknown mechanism of immunoglobulin G2 appearance in colostrum is occurring. Finally, no measured protein exhibited any correlation with the activity of lactate dehydrogenase in colostrum.

Keywords

ColostrumIgGBSAquarter variation
Type
Research Article
Information
Journal of Dairy Research , Volume 83 , Issue 2 , May 2016 , pp. 209 - 218
Copyright
Copyright © Proprietors of Journal of Dairy Research 2016 

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