Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-29T15:36:38.056Z Has data issue: false hasContentIssue false

Influence of postoperative pain and use of NSAID on heart rate variability of dairy cows

Published online by Cambridge University Press:  22 February 2018

Lilli Frondelius*
Affiliation:
Natural Resources Institute Finland (Luke), Production Systems, Halolantie 31 A, 71750 Maaninka, Finland
Juha Hietaoja
Affiliation:
Department of Agricultural Sciences, Faculty of Agriculture and Forestry, University of Helsinki, P.O Box 28, 00014 University of Helsinki, Finland
Matti Pastell
Affiliation:
Natural Resources Institute Finland (Luke), Production Systems, Halolantie 31 A, 71750 Maaninka, Finland
Laura Hänninen
Affiliation:
Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 57, 00014 University of Helsinki, Finland
Paula Anttila
Affiliation:
Maalaiseläinlääkäri Anttila, Halolantie 27, 71750 Maaninka, Finland
Jaakko Mononen
Affiliation:
Natural Resources Institute Finland (Luke), Production Systems, Halolantie 31 A, 71750 Maaninka, Finland
*
*For correspondence; e-mail: [email protected]

Abstract

This Research Communication describes the effect of post-operative pain and non-steroidal anti-inflammatory drug (NSAID) treatment on heart rate variability (HRV) of dairy cows. Postoperative pain in farm animals is often left untreated, and HRV could be a promising tool for assessing pain. The aim of this study was to assess if postoperative state after subcutaneous surgery affects HRV in dairy cows and to determine whether this could be modulated by NSAID. Nine cows were inserted with an implantable electrocardiograph logger. Cows were divided into the NSAID treatment group and the control group. The cows in the NSAID group had higher HRV than the control group, indicating a higher sympathetic activity in control animals, most likely due to untreated post-operative pain. Besides the ethical need for treating pain in production animals, ongoing pain has an adverse effect on animal productivity. Thus post-operative pain alleviation is recommended.

Type
Research Article
Copyright
Copyright © Hannah Dairy Research Foundation 2018 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Anil, L, Anil, SS & Deen, J 2005 Pain detection and amelioration in animals on the farm: issues and options. Journal of Applied Animal Welfare Science 8 261278 Google Scholar
Banting, A, Banting, S, Heinonen, K & Mustonen, K 2008 Efficacy of oral and parenteral ketoprofen in lactating cows with endotoxin-induced acute mastitis. Veterinary Record 163 506509 Google Scholar
Bjarnason, Á, Vuorela, T, Verho, J, Riistama, J, Vanhala, J, Lekkala, J & Hyttinen, J 2013 Implantable measurement system for dairy-cattle monitoring with long recording time. Advances in Science and Technology 85 3338 Google Scholar
Donalisio, C, Barbero, R, Cuniberti, B, Vercelli, C, Casalone, M & Re, G 2012 Effects of flunixin meglumine and ketoprofen on mediator production in ex vivo and in vitro models of inflammation in healthy dairy cows. Journal of Veterinary Pharmacology and Therapeutics 36 130139 CrossRefGoogle Scholar
Frondelius, L, Järvenranta, K, Koponen, T & Mononen, J 2015 The effects of body posture and temperament on heart rate variability in dairy cows. Physiology & Behavior 139 437441 Google Scholar
Newby, NC, Tucker, CB, Pearl, DL, LeBlanc, SJ, Leslie, KE, von Keyserlingk, MAG, Duffield, TF 2014 An investigation of the effects of ketoprofen following rumen fistulation surgery in lactating dairy cows. The Canadian Veterinary Journal 55 442448 Google Scholar
Raekallio, M, Taylor, PM & Bennett, RC 1997 Preliminary investigations of pain and analgesia assessment in horses administered phenylbutazone or placebo after arthroscopic surgery. Veterinary Surgery 26 150155 Google Scholar
Stewart, M, Stafford, KJ, Dowling, SK, Scaefer, AL & Webster, JR 2008 Eye temperature and heart rate variability of calves disbudded with or without local anaesthetic. Physiology & Behaviour 93 789797 Google Scholar
Stewart, M, Verkert, GA, Stafford, KJ, Schaefer, AL & Webster, JR 2010 Noninvasive assessment of autonomic activity for evaluation of pain in calves, using surgical castration as a mode. Journal of Dairy Science 96 36023609 Google Scholar
Stubsjøen, SM, Flø, AS, Moe, RO, Janczak, AM, Skjerve, E, Valle, PS & Zanella, AJ 2009 Exploring non-invasive methods to assess pain in sheep. Physiology & Behaviour 98 640648 CrossRefGoogle ScholarPubMed
Task Force of The European Society of Cardiology, North American Society of Pacing and Electrophysiology 1996 Heart rate variability – standards of measurement, physiological interpretation, and clinical use. Circulation 93 10431065 Google Scholar
Tiusanen, J & Pastell, M 2016 Simple online algorithm for detecting cow's ECG beat-to-beat interval using a microcontroller. Agricultural Engineering International: CIGR Journal 18 411418 Google Scholar
Tiusanen, J, Hautala, MI, Ternman, EM & Pastell, ME 2015 Geometrical method for interpolating S-peaks from cow ECG using a microcontroller. Biosystems Engineering 129 324328 Google Scholar
Viñuela-Fernández, I, Jones, E, Welsh, EM & Fleetwood-Walker, SM 2007 Pain mechanism and their implication for the management of pain in farm and companion animals. The Veterinary Journal 174 227239 CrossRefGoogle ScholarPubMed
Von Borell, E, Langbein, J, Deprés, G, Hansen, S, Leterrier, C, Marchant-Forde, J, Marchand-Forde, R, Minero, M, Mohr, E, Prunier, A, Valance, D & Veissier, I 2007 Heart rate variability as a measure of autonomic regulation of cardiac activity for assessing stress and welfare in farm animals – a review. Physiology & Behavior 92 293316 Google Scholar
Walker, KA, Duffield, TF & Weary, DM 2011 Identifying and preventing pain during and after surgery in farm animals. Applied Animal Behaviour Science 135 259265 Google Scholar