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Examination of an antibiotic produced by coagulase-negative staphylococci isolated from the bovine udder

Published online by Cambridge University Press:  01 June 2009

G. W. Jones  and
S. J. Edwards
G. W. Jones
Affiliation:
Agricultural Research Council, Institute for Research on Animal DiseasesCompton, Newbury, Berks
S. J. Edwards
Affiliation:
Agricultural Research Council, Institute for Research on Animal DiseasesCompton, Newbury, Berks
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Summary

An antibiotic produced by coagulase-negative staphylococci isolated from the bovine udder was examined by deferred antagonism tests and its inhibitory properties compared with those of other staphylococci. While inhibiting the growth of representative phage types of bovine pathogenic staphylococci, its activity against corynebacteria was more restricted than that of Staphylococcus aureus NCTC 6507 and 8004. Only minimal amounts of inhibitory substance were produced in liquid media, larger amounts were produced on solid media and the incorporation of a blood plasma factor further increased production. The inhibitory substance resisted treatment with pepsin and trypsin and withstood boiling for 30 min. Its characters in relation to inhibitory substances produced by other staphylococci are discussed.

Type
Original Articles
Information
Journal of Dairy Research , Volume 33 , Issue 3 , October 1966 , pp. 271 - 276
Copyright
Copyright © Proprietors of Journal of Dairy Research 1966

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References

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