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Effect of thiocyanate on mammary gland growth in rats

Published online by Cambridge University Press:  01 June 2009

H. Pyska
H. Pyska
Affiliation:
Department of Animal Physiology, Zootechnical Institute, 31–047 Cracow, Poland
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Summary

In growing rats from 3 weeks to 3 months old, 0·1 % potassium thiocyanate (KSCN) decreased the plasma protein-bound iodine level by 47 % and the total DNA in the mammary gland by 11 %, but had no effect on the total KNA. Administration of thiocyanate in the form of 0·1, 0·3 and 0·5 % KSCN during pregnancy and 14 d of lactation lowered the protein-bound iodine level by 48–66 %, the total DNA by 11–47 % and the total RNA by 14–63 %, depending on the KSCN dosage. The 14-d-old litters of rats receiving thiocyanate weighed 4–41 % less than those in the control group.

Type
Original Articles
Information
Journal of Dairy Research , Volume 44 , Issue 3 , October 1977 , pp. 427 - 431
Copyright
Copyright © Proprietors of Journal of Dairy Research 1977

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