Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-26T15:41:39.676Z Has data issue: false hasContentIssue false
  • English
  • Français

Effect of Escherichia coli endotoxin-mediated inflammation of one mammary quarter of the bovine udder on diapedesis into other quarters

Published online by Cambridge University Press:  01 June 2009

W. Donald Schultze  and
A. John Bramley
W. Donald Schultze
Affiliation:
National Institute for Research in Dairying, Shinfield, Reading RG2 9 AT, UK
A. John Bramley
Affiliation:
National Institute for Research in Dairying, Shinfield, Reading RG2 9 AT, UK
Get access Rights & Permissions [Opens in a new window]

Summary

Implantation of 1 μg Escherichia coli endotoxin into one papillary duct of a bovine udder frequently resulted in a mild inflammatory process in the treated quarter which was measured by use of the Wisconsin mastitis test (WMT) on quarter fore milk samples. Inflammation of a fore quarter was usually (18/24) accompanied by a transient elevation in WMT score from the homolateral hind quarter, but rarely (1/25) from the contralateral quarter. Inflammation in a hind quarter rarely (2/26) affected the homolateral fore quarter and never (0/25) the contralateral quarter. The pattern of responses suggests that absorption and initial removal of endotoxin from the mammary gland occurs via the lymphatic rather than the blood system.

Type
Original Articles
Information
Journal of Dairy Research , Volume 49 , Issue 3 , August 1982 , pp. 381 - 385
Copyright
Copyright © Proprietors of Journal of Dairy Research 1982

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Brownlie, J. 1979 The effect of an intramammary infusion of endotoxin on the establishment of experimental mastitis byStreptococcus agalactiae in the cow. Journal of Hygiene 83 103–109.CrossRefGoogle ScholarPubMed
Carroll, E. J., Schalm, O. W., & Lasmanis, J. 1964 Experimental coliform (Aerobacter aerogenes) mastitis: characteristics of the endotoxin and its role in pathogenesis. American Journal of Veterinary Research 25 720–726.Google ScholarPubMed
Dhondt, G., Burvenich, C. & Peeters, G. 1977 Mammary blood flow during experimental Escherichia coli endotoxin induced mastitis in goats and cows. Journal of Dairy Research 44 433–440CrossRefGoogle ScholarPubMed
M.El Hagri, M. A. A. El Hagri, M. A. A. 1945 Study of the arterial and lymphatic systems in the udder of the cow Il. Veterinary Journal 101 51–63.Google Scholar
Jain, N. C., Schalm, O. W. & Lasmanis, J. 1978 Neutrophil kinetics in endotoxin-induced mastitis. American Journal of Veterinary Research 39 1662–1667.Google ScholarPubMed
Linzell, J. L. 1960 Valvular incompetence in the venous drainage of the udder. Journal of Physiology 153 481–491.CrossRefGoogle ScholarPubMed
Paape, M. J., Schultze, W. D., Desjardins, C. & Miller, R. H. 1974 Plasma corticosteroid, circulating leukocyte and milk somatic cell response to Escherichia coli endotoxin-induced mastitis. Proceedings of the Society for Experimental Biology and Medicine 145 553–559.CrossRefGoogle ScholarPubMed
Rasmussen, F. 1972 The mechanism of excretion of drugs into milk from untreated glands after intramammary application. Acta Veterinaria Scandinavica 13 275–277.CrossRefGoogle ScholarPubMed
Schalm, O. W. & Ziv-Silberman, G. 1968 Reactions following intramammary infusion of E. coli endotoxin. Veterinary Record 82 100–103.Google Scholar
Schultze, W. D. 1973 Comparison of indirect procedures for estimating somatic cell concentration. Journal of Dairy Science 56 331–336.CrossRefGoogle Scholar
Schultze, W. D. 1981 Assay of penetrability of bovine papillary duct implanted with Escherichia coli endotoxin. American Journal of Veterinary Research 42 1993–1998.Google ScholarPubMed
Swett, W. W. & Matthews, C. A. 1949 Some studies of the circulatory system of the cow's udder. Technical Bulletin USDA no. 982 36 pp.Google Scholar
U.S. Department of Health, Education and Welfare, Public Health Service 1970 Guidelines for the control of abnormal milk. Washington DC: U.S. Government Printing Office.Google Scholar
Yoffey, J. M. & Courtice, F. C. 1970 Lymphatics, Lymph and the Lymphomyeloid Complex. New York: Academic PressGoogle Scholar
Ziv, G., Gordin, S. & Bechar, G. 1974 Mode of transfer of antibiotics from treated to nontreated quarters in dairy cows. American Journal of Veterinary Research 35 643–647Google ScholarPubMed
Ziv, G., Hartman, I., Booin, E., Abidar, J. & Saran, A. 1976 Endotoxin in blood and milk and enzymes in milk of cows during experimental E. coli endotoxin mastitis. Theriogenology 6 343–352CrossRefGoogle Scholar