Hostname: page-component-cd9895bd7-q99xh Total loading time: 0 Render date: 2024-12-23T03:31:49.610Z Has data issue: false hasContentIssue false
  • English
  • Français

Changes of macrominerals and calcitropic hormones in serum of periparturient dairy cows subject to subclinical hypocalcaemia

Published online by Cambridge University Press:  22 February 2018

Chuanjiang Cai ,
Yezi Kong ,
Dianjun Wu  and
Jianguo Wang
Chuanjiang Cai
Affiliation:
College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China
Yezi Kong
Affiliation:
College of Veterinary Medicine, Northwest A&F University, Yangling 712100, Shaanxi, China
Dianjun Wu
Affiliation:
Department of Clinical Science, College of Veterinary Medicine, Jilin University, Changchun 130062, Jilin, China
Jianguo Wang*
Affiliation:
College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China College of Veterinary Medicine, Northwest A&F University, Yangling 712100, Shaanxi, China
*
*For correspondence; e-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

The aims of the study reported in the Research Communication were to evaluate changes of macrominerals and major calcitropic hormone concentrations in 51 healthy dairy cows over the peripartum period, and to compare those cows with 51 cows subject to subclinical hypocalcaemia (SCH) on calving day. The results showed that serum calcium (Ca) and potassium (K) concentrations were lowest in the healthy periparturient dairy cows at parturition, while sodium (Na) and parathyroid hormone (PTH) concentrations were highest. Serum magnesium (Mg), chloride (Cl) and phosphorus (P) concentrations were highest 1 wk prepartum, however, the concentration of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] was highest 1 wk postpartum. The dairy cows with subclinical hypocalcaemia (SCH) had significantly lower serum levels of Ca, K, Na, Mg, Cl, 1,25(OH)2D3 and glucose and had significantly higher levels of serum P, non-esterified fatty acids (NEFA) and β-hydroxybutyrate (BHBA) than their healthy counterparts on calving day. However, the serum calcitonin and PTH concentrations were not significantly different between the two groups. These data demonstrated that the concentrations of macrominerals and major calcium regulating hormones of cows change dramatically over the peripartum period. Furthermore, SCH was associated with a risk of the development of ketosis and fatty liver.

Keywords

Metabolic disorderHomoeostatic1,25(OH)2D3PTHPeripartum
Type
Research Article
Information
Journal of Dairy Research , Volume 85 , Issue 1 , February 2018 , pp. 12 - 15
Copyright
Copyright © Hannah Dairy Research Foundation 2018 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Chan, PS, West, JW & Bernard, JK 2006 Effect of prepartum dietary calcium on intake and serum and urinary mineral concentrations of cows. Journal of Dairy Science 89 704–713 CrossRefGoogle ScholarPubMed
Degaris, PJ & Lean, IJ 2008 Milk fever in dairy cows: a review of pathophysiology and control principles. Veterinary Journal 176 58–69 CrossRefGoogle ScholarPubMed
Du, X, Shi, Z, Peng, Z, Zhao, C, Zhang, Y, Wang, Z, Li, X, Liu, G & Li, X 2017 Acetoacetate induces hepatocytes apoptosis by the ROS-mediated MAPKs pathway in ketotic cows. Journal of Cellular Physiology 232 3296–3308 Google Scholar
Goff, JP 2008 The monitoring, prevention, and treatment of milk fever and subclinical hypocalcemia in dairy cows. Veterinary Journal 176 50–57 CrossRefGoogle ScholarPubMed
Heppelmann, M, Krach, K, Krueger, L, Benz, P, Herzog, K, Piechotta, M, Hoedemaker, M & Bollwein, H 2015 The effect of metritis and subclinical hypocalcemia on uterine involution in dairy cows evaluated by sonomicrometry. Journal of Reproduction and Development 61 565–569 Google Scholar
Reinhardt, TA, Lippolis, JD, Mccluskey, BJ, Goff, JP & Horst, RL 2011 Prevalence of subclinical hypocalcemia in dairy herds. Veterinary Journal 188 122–124 Google Scholar
Roche, J & Berry, D 2006 Periparturient climatic, animal, and management factors influencing the incidence of milk fever in grazing systems. Journal of Dairy Science 89 2775–2783 Google Scholar
Rodriquez, EM, Bach, A, Devant, M & Aris, A 2016 Is calcitonin an active hormone in the onset and prevention of hypocalcemia in dairy cattle? Journal of Dairy Science 99 3023–3030 Google Scholar
Song, Y, Li, N, Gu, J, Fu, S, Peng, Z, Zhao, C, Zhang, Y, Li, X, Wang, Z, Li, X & Liu, G 2016 β-Hydroxybutyrate induces bovine hepatocyte apoptosis via an ROS-p38 signaling pathway. Journal Dairy Science 99 9184–9198 CrossRefGoogle ScholarPubMed
Wang, J, Zhu, X, Chen, C, Li, X, Gao, Y, Li, P, Zhang, Y, Long, M, Wang, Z & Liu, G 2012 Effect of insulin-like growth factor-1 (IGF-1) on the gluconeogenesis in calf hepatocytes cultured in vitro. Molecular and Cellular Biochemistry 362 87–91 Google Scholar
Supplementary material: PDF

Cai et al. supplementary material

Tables S1-S2

Download Cai et al. supplementary material(PDF)
PDF 31.7 KB