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Changes in the concentrations of metabolites in milk at the onset and cessation of lactation in the goat

Published online by Cambridge University Press:  01 June 2009

Anne Faulkner ,
David R. Blatchford ,
Jann M. White  and
Malcolm Peaker
Anne Faulkner
Affiliation:
Hannah Research Institute, Ayr, Scotland KA6 5HL
David R. Blatchford
Affiliation:
Hannah Research Institute, Ayr, Scotland KA6 5HL
Jann M. White
Affiliation:
Hannah Research Institute, Ayr, Scotland KA6 5HL
Malcolm Peaker
Affiliation:
Hannah Research Institute, Ayr, Scotland KA6 5HL
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Summary

Changes in the concentrations of various metabolites in mammary secretions (organic acids, UDP-hexoses and nucleotides) have been observed at the onset and cessation of lactation. All metabolites, with the exception of galactose, increased dramatically in concentration just before and immediately after parturition. Galactose concentrations decreased with the onset of lactation. After regular milking ceased, the concentrations of these metabolites in milk contained within the udder fell, but the rates of decline varied.

Type
Original Articles
Information
Journal of Dairy Research , Volume 49 , Issue 3 , August 1982 , pp. 399 - 405
Copyright
Copyright © Proprietors of Journal of Dairy Research 1982

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References

REFERENCES

Baldwin, R. L. & Milligan, L. P. 1966 Enzymatic changes associated with the initiation and maintenance of lactation in the rat. Journal of Biological Chemistry 241 2058–2066CrossRefGoogle ScholarPubMed
Emerman, J. T., Bartley, J. C. & Bissell, M. J. 1980 Interrelationship of glycogen metabolism and lactose synthesis in mammary epithelial cells of mice. Biochemical Journal 192 695–702CrossRefGoogle ScholarPubMed
Faulkner, A. 1980 The presence of cellular metabolites in milk. Biochimica el Biophysica Acta 630 141–145CrossRefGoogle ScholarPubMed
Faulkner, A., Chaiyabutr, N., Peaker, M., Carrick, D. T. & Kuhn, N. J. 1981 Metabolic significance of milk glucose. Journal of Dairy Research 48 51–56CrossRefGoogle ScholarPubMed
Fleet, I. R., Goode, J. A., Hamon, M. H., Laurie, M. S., Linzell, J. L. & Peaker, M. 1975 Secretory activity of goat mammary glands during pregnancy and the onset of lactation. Journal of Physiology 251 763–773CrossRefGoogle ScholarPubMed
Fleet, I. R. & Peaker, M. 1978 Mammary function and its control at the cessation of lactation in the goat. Journal of Physiology 279 491–507CrossRefGoogle ScholarPubMed
Jenness, R. 1974 The composition of milk. In Lactation: A Comprehensive Treatise 3 pp. 3–107 (Eds Larson, B. L. and Smith, V. R.) New York: Academic PressGoogle Scholar
Johke, T. 1978 Nucleotides of mammary secretions. In Lactation: A Comprehensive Treatise 4 pp. 513–522 (Ed. Larson, B. L.) New York: Academic Press.Google Scholar
Kuhn, N. J. & White, A. 1975 The topography of lactose synthesis. 148 77–84Google ScholarPubMed
Kuhn, N. J. & White, A. 1976 Evidence for specific transport of uridine diphosphate galactose across the Golgi membrane of rat mammary gland. Biochemical Journal 154 243–244CrossRefGoogle ScholarPubMed
Linzell, J. L., Mepham, T. B. & Peaker, M. 1976 The secretion of citrate into milk. Journal of Physiology 260 739–750CrossRefGoogle ScholarPubMed
Peaker, M., Faulkner, A. & Blatchford, D. R. 1981 Changes in milk citrate concentration during lactation in the goat. Journal of Dairy Research 48 357–361CrossRefGoogle ScholarPubMed
Peaker, M. & Linzell, J. L. 1975 Citrate in milk: a harbinger of lactogenesis. Nature 253 464CrossRefGoogle ScholarPubMed
Waldschmidt, M. & Rilling, S. 1973 Metabolite levels and enzyme activities in the bovine mammary gland in different stages of lactation. II. Some metabolite levels and enzyme activities of the citric acid cycle. Journal of Dairy Research 40 361–370CrossRefGoogle Scholar