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Effect of atropine on plasma amino acid levels and milk secretion of cows

Published online by Cambridge University Press:  01 June 2009

Eddy Roets  and
Georges Peeters
Eddy Roets
Affiliation:
Department of Physiology, Veterinary Faculty of the University of Ghent, Casinoplein 24, B-9000 Ghent, Belgium
Georges Peeters
Affiliation:
Department of Physiology, Veterinary Faculty of the University of Ghent, Casinoplein 24, B-9000 Ghent, Belgium
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Summary

Subcutaneous injections of 30 mg atropine into lactating cows induced a 20–40% decrease of free amino acid (AA) levels in arterial plasma. Minimum levels were observed after 30–50 min. The decline persisted for more than 6 h. The greatest fall in concentration was noted for tyrosine, methionine, lysine, arginine, phenylalanine and threonine. Arterial glucose levels remained unaffected. The effect of atropine on milk secretion was studied in 2 cows which were milked every hour with the aid of oxytocin. Maximal effects were observed after 3–4 h. They included reduction in concentration of casein and ±-lactalbumin (±-la) and a decline in production of milk (20%), casein (35%), ±-la (45%) and lactose (18%). Uptake by the lactating udder over a period of about 1 h after injection of atropine was studied in 2 cows. Mammary blood flow and glucose uptake remained unaffected. There was a positive correlation between arteriovenous differences of essential AA and arterial plasma concentrations. The uptake of essential AA decreased by approximately 50 %. There was no evidence that atropine has a direct inhibiting effect on the udder. It is suggested that the decrease of ±-la synthesis might induce an inhibition of lactose synthesis and milk production.

Type
Original Articles
Information
Journal of Dairy Research , Volume 48 , Issue 1 , February 1981 , pp. 23 - 34
Copyright
Copyright © Proprietors of Journal of Dairy Research 1981

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