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428. The acid phosphatase of mammary tissue of the cow and the rat
Published online by Cambridge University Press: 01 June 2009
Extract
1. Mammary tissue of the cow and the rat contains acid phosphatase. The respective pH optima are 5·5–5·8 and 6·0.
2. The enzyme in cow mammary tissue is probably one of type AII in the Folley & Kay (10) classification.
3. The acid phosphatase of cow mammary tissue is inhibited by a factor in raw cows' milk. This factor is destroyed by heat.
4. On the basis of rate of hydrolysis of phenylphosphate at the optimum pH there is about 5 times more alkaline phosphatase in the mammary tissue of the cow than acid phosphatase.
5. The effect of adrenalectomy and replacement therapy through the administration of cortical steroids has no marked effect on the acid phosphatase of rat mammary tissue.
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