Hostname: page-component-586b7cd67f-2brh9 Total loading time: 0 Render date: 2024-11-22T20:56:29.713Z Has data issue: false hasContentIssue false
  • English
  • Français

UNDERSTANDING ETHNIC DIFFERENCES IN BEHAVIOUR RELATING TO SCHISTOSOMA MANSONI RE-INFECTION AFTER MASS TREATMENT

Published online by Cambridge University Press:  22 November 2010

ANGELA PINOT DE MOIRA ,
NARCIS B. KABATEREINE ,
DAVID W. DUNNE  and
MARK BOOTH
ANGELA PINOT DE MOIRA
Affiliation:
Department of Pathology, University of Cambridge, Cambridge, UK
NARCIS B. KABATEREINE
Affiliation:
Vector Control Division, Ministry of Health, Kampala, Uganda
DAVID W. DUNNE
Affiliation:
Department of Pathology, University of Cambridge, Cambridge, UK
MARK BOOTH
Affiliation:
Department of Pathology, University of Cambridge, Cambridge, UK Wolfson Research Institute, Durham University, UK
Get access Rights & Permissions [Opens in a new window]

Summary

It is now widely recognized that a decentralized approach to the control of parasitic infections in rural sub-Saharan populations allows for the design of more effective control programmes and encourages high compliance. Compliance is usually an indicator of treatment success, but cannot be used as a measure of long-term benefit since re-infection will be strongly influenced by a number of factors including the social ecology of a community. In this paper qualitative and quantitative methods are used to identify and understand the structural and behavioural constraints that may influence water contact behaviour and create inequalities with respect to Schistosoma re-infection following anti-helminth drug treatment. The research is set in a community where participant engagement has remained uniformly high throughout the course of a 10-year multidisciplinary study on treatment and re-infection, but where levels of re-infection have not been uniform and, because of variations in water contact behaviour, have varied by age, sex and ethnic background. Variations in the biomedical knowledge of schistosomiasis, socioeconomic constraints and ethnic differences in general attitudes towards life and health are identified that may account for some of these behavioural differences. The observations highlight the benefits of understanding the socio-ecology of control and research settings at several levels (both between and within ethnic groups); this will help to design more effective and universally beneficial interventions for control and help to interpret research findings.

Type
Research Article
Information
Journal of Biosocial Science , Volume 43 , Issue 2 , March 2011 , pp. 185 - 209
Copyright
Copyright © Cambridge University Press 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Barbosa, C. S. (1998) Epidemiology and anthropology: an integrated approach dealing with bio-socio-cultural aspects as strategy for the control of endemic diseases. Memorias do Instituto Oswaldo Cruz 93 (Supplement 1), 59–62.CrossRefGoogle ScholarPubMed
Booth, M., Vennervald, B. J., Kabatereine, N. B., Kazibwe, F., Ouma, J. H., Kariuki, C. H. et al. (2004) Hepatosplenic morbidity in two neighbouring communities in Uganda with high levels of Schistosoma mansoni infection but very different durations of residence. Transactions of the Royal Society of Tropical Medicine and Hygiene 98, 125–136.CrossRefGoogle ScholarPubMed
Boyle, M. H., Racine, Y., Georgiades, K., Snelling, D., Hong, S., Omariba, W. et al. (2006) The influence of economic development level, household wealth and maternal education on child health in the developing world. Social Science & Medicine 63, 2242–2254.CrossRefGoogle ScholarPubMed
Brady, M. A., Hooper, P. J. & Ottesen, E. A. (2006) Projected benefits from integrating NTD programs in sub-Saharan Africa. Trends in Parasitology 22, 285–291.CrossRefGoogle ScholarPubMed
Cleland, J. G. & Van Ginneken, J. K. (1988) Maternal education and child survival in developing countries: the search for pathways of influence. Social Science & Medicine 27, 1357–1368.CrossRefGoogle ScholarPubMed
De Silva, N. R., Jayapani, V. P. & De Silva, H. J. (1996) Socioeconomic and behavioral factors affecting the prevalence of geohelminths in preschool children. Southeast Asian Journal of Tropical Medicine and Public Health 27, 36–42.Google ScholarPubMed
Dunne, D. W., Vennervald, B. J., Booth, M., Joseph, S., Fitzsimmons, C. M., Cahen, P. et al. (2006) Applied and basic research on the epidemiology, morbidity, and immunology of schistosomiasis in fishing communities on Lake Albert, Uganda. Transactions of the Royal Society of Tropical Medicine and Hygiene 100, 216–223.CrossRefGoogle ScholarPubMed
Garba, A., Toure, S., Dembele, R., Bosque-Oliva, E. & Fenwick, A. (2006) Implementation of national schistosomiasis control programmes in West Africa. Trends in Parasitology 22, 322–326.CrossRefGoogle ScholarPubMed
Geissler, P. W., Kelly, A., Imoukhuede, B. & Pool, R. (2008) ‘He is now like a brother, I can even give him some blood' – relational ethics and material exchanges in a malaria vaccine ‘trial community’ in The Gambia. Social Science & Medicine 67, 696–707.CrossRefGoogle Scholar
Guo, J. G., Cao, C. L., Hu, G. H., Lin, H., Li, D., Zhu, R. & Xu, J. (2005) The role of ‘passive chemotherapy’ plus health education for schistosomiasis control in China during maintenance and consolidation phase. Acta Tropica 96, 177–183.CrossRefGoogle Scholar
Hotez, P. J., Molyneux, D. H., Fenwick, A., Ottesen, E., Ehrlich Sachs, S. & Sachs, J. D. (2006) Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV/AIDS, tuberculosis, and malaria. PLoS Medicine 3, e102.CrossRefGoogle ScholarPubMed
Huang, Y. X. & Manderson, L. (2005) The social and economic context and determinants of schistosomiasis japonica. Acta Tropica 96, 223–231.Google ScholarPubMed
Kabatereine, N. B., Brooker, S., Koukounari, A., Kazibwe, F., Tukahebwa, E. M., Fleming, F. M. et al. (2007) Impact of a national helminth control programme on infection and morbidity in Ugandan schoolchildren. Bulletin of the World Health Organization 85, 91–99.Google ScholarPubMed
Kabatereine, N. B., Fleming, F. M., Nyandindi, U., Mwanza, J. C. & Blair, L. (2006) The control of schistosomiasis and soil-transmitted helminths in East Africa. Trends in Parasitology 22, 332–339.CrossRefGoogle ScholarPubMed
Kabatereine, N. B., Kariuki, C. H., Kazibwe, F., Kemijumbi, J., Sturrock, R., Ornbjerg, N. & Madsen, H. (1999) Snail related aspects of transmission of Schistosoma mansoni at Butiaba, Lake Albert, North Western Uganda. In Proceedings of Workshop on Medical and Veterinary Malacology in Africapp. 141–154. Harare, Zimbabwe.Google Scholar
Katz, N., Chaves, A. & Pellegrino, J. (1972) A simple device for quantitative stool thick-smear technique in Schistosomiasis mansoni. Revista do Instituto de Medicina Tropical de Sao Paulo 14, 397–400.Google ScholarPubMed
Kazibwe, F., Makanga, B., Rubaire-Akiiki, C., Ouma, J., Kariuki, C., Kabatereine, N. B. et al. (2006) Ecology of Biomphalaria (Gastropoda: Planorbidae) in Lake Albert, Western Uganda: snail distributions, infection with schistomes and temporal associations with environmental dynamics. Hydrobiologia 568, 433–444.CrossRefGoogle Scholar
Kazibwe, F., Makanga, B., Rubaire-Akiiki, C., Ouma, J., Kariuki, C., Kabatereine, N. B. et al. (2010) Transmission studies of intestinal schistosomiasis in Lake Albert, Uganda and experimental compatibility of local Biomphalaria spp. Parasitology International 59, 49–53.CrossRefGoogle ScholarPubMed
Kloos, H., Ouma, J., Kariuki, H. C. & Butterworth, A. E. (1986) Knowledge, perceptions and health behavior pertaining to Schistosoma mansoni related illness in Machakos district, Kenya. Tropical Medicine and Parasitology 37, 171–175.Google ScholarPubMed
Kloos, H., Ouma, J. H., Kariuki, H. C. & Butterworth, A. E. (1987) Coping with intestinal illness among the Kamba in Machakos, Kenya, and aspects of schistosomiasis control. Social Science & Medicine 24, 383–394.CrossRefGoogle ScholarPubMed
Kolaczinski, J. H., Kabatereine, N. B., Onapa, A. W., Ndyomugyenyi, R., Kakembo, A. S. & Brooker, S. (2007) Neglected tropical diseases in Uganda: the prospect and challenge of integrated control. Trends in Parasitology 23, 485–493.CrossRefGoogle ScholarPubMed
Leopold, M. (2005) ‘Why are we cursed?’: Writing history and making peace in north west Uganda. Journal of the Royal Anthropological Institute 11, 211–229.CrossRefGoogle Scholar
Leopold, M. (2006) Legacies of slavery in north-west Uganda: the story of the ‘one-elevens'. Africa 76, 180–199.CrossRefGoogle Scholar
Mehanna, S., Winch, P. J., Rizkalla, N. H., El-Sayed, H. F. & Abaza, S. M. (1997) Factors affecting knowledge of the symptoms of schistosomiasis in two rural areas near Ismailia, Egypt. Tropical Medicine & International Health 2, A36–47.Google ScholarPubMed
Meinert, L. (2004) Resources for health in Uganda: Bourdieu's concept of capital and habitus. Anthropology and Medicine 11, 11–26.CrossRefGoogle ScholarPubMed
Michelson, E. H. (1993) Adam's rib awry? Women and schistosomiasis. Social Science & Medicine 37, 493–501.CrossRefGoogle ScholarPubMed
Molyneux, D. H., Hotez, P. J. & Fenwick, A. (2005) “Rapid-impact interventions”: how a policy of integrated control for Africa's neglected tropical diseases could benefit the poor. PLoS Medicine 2, e336.CrossRefGoogle ScholarPubMed
Morgan, D. L. (1996) Focus Groups as Qualitative Research. Sage Publications, London.Google Scholar
Parker, M. (1993) Bilharzia and the boys: questioning common assumptions. Social Science & Medicine 37, 481–492.CrossRefGoogle ScholarPubMed
Parker, M., Allen, T. & Hastings, J. (2007) Resisting control of neglected tropical diseases: dilemmas in the mass treatment of schistosomiasis and soil-transmitted helminths in north-west Uganda. Journal of Biosocial Science 40, 161–181.CrossRefGoogle ScholarPubMed
Pinot De Moira, A., Fulford, A. J., Kabatereine, N. B., Kazibwe, F., Ouma, J. H., Dunne, D. W. & Booth, M. (2007) Microgeographical and tribal variations in water contact and Schistosoma mansoni exposure within a Ugandan fishing community. Tropical Medicine & International Health 12, 724–735.CrossRefGoogle ScholarPubMed
Pinot DeMoira, A. Moira, A., Fulford, A. J., Kabatereine, N. B., Ouma, J. H., Booth, M. & Dunne, D. W. (2010) Analysis of complex patterns of human exposure and immunity to Schistosomiasis mansoni: the influence of age, sex, ethnicity and IgE. PLoS Neglected Tropical Diseases 4, e820.CrossRefGoogle Scholar
Southall, A. (1953) Alur Society: A Study in Processes and Types of Domination. W. Heffer and Sons Ltd, Cambridge.Google Scholar
Southall, A. (1998) Isolation and underdevelopment: periphery and centre. In Hansen, H. B. & Twaddle, M. (eds) Developing Uganda. James Curry, Oxford.Google Scholar
Steering Committee for Cooperative Action (1990) The IDWSSD and Women's Involvement, p. 22. World Health Organization, Geneva.Google Scholar
UNICEF/Government of Uganda (1997) Implementing Universal Primary Education (UPE): Enrollment and Registration. Government of Uganda, Kampala.Google Scholar
Vlassoff, C. & Bonilla, E. (1994) Gender-related differences in the impact of tropical diseases on women: what do we know? Journal of Biosocial Science 26, 37–53.CrossRefGoogle ScholarPubMed
Walter, K., Fulford, A. J., Mcbeath, R., Joseph, S., Jones, F. M., Kariuki, H. C. et al. (2006) Increased human IgE induced by killing Schistosoma mansoni in vivo is associated with pretreatment Th2 cytokine responsiveness to worm antigens. Journal of Immunology 177, 5490–5498.CrossRefGoogle ScholarPubMed
Wamani, H., Tylleskar, T., Astrom, A. N., Tumwine, J. K. & Peterson, S. (2004) Mothers' education but not fathers' education, household assets or land ownership is the best predictor of child health inequalities in rural Uganda. International Journal of Equity Health 3, 9.CrossRefGoogle ScholarPubMed
World Health Organization (2002) Prevention and Control of Schistosomiasis and Soil-Transmitted Helminthiasis. World Health Organization Expert Committee, Geneva.Google Scholar
Zhang, Y., Koukounari, A., Kabatereine, N., Fleming, F., Kazibwe, F., Tukahebwa, E. et al. (2007) Parasitological impact of 2-year preventive chemotherapy on schistosomiasis and soil-transmitted helminthiasis in Uganda. BMC Medicine 5, 27.CrossRefGoogle ScholarPubMed