Hostname: page-component-745bb68f8f-g4j75 Total loading time: 0 Render date: 2025-01-09T22:43:34.736Z Has data issue: false hasContentIssue false
  • English
  • Français

Tylosis in the Orkney Islands

Published online by Cambridge University Press:  31 July 2008

Veronica M. L. Muir
Veronica M. L. Muir
Affiliation:
Department of Human Biology and Health, University of Survey, Guildford
Get access Rights & Permissions [Opens in a new window]

Summary

The familial condition of tylosis was found in a single extended family in the Orkney islands. Unlike other pedigrees described it has no association with carcinoma of the oesophagus. Various linkage studies have been suggested and pooling of available data would offer a more constructive approach. Electron microscopy suggests further biochemical analysis on affected and normal skin to elucidate the underlying factors causing hyperkeratinization, and possibly resulting in more sophisticated treatment for this irritable but harmless condition.

Type
Research Article
Information
Journal of Biosocial Science , Volume 10 , Issue 1 , January 1978 , pp. 1 - 6
Copyright
Copyright © Cambridge University Press 1978

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Cockayne, E.A. (1933) Inherited Abnormalities of the Skin and its Appendages. Oxford University Press, London.Google Scholar
Harper, P.S., Harper, R.M.J. & Howel-Evans, A.W. (1970) Carcinoma of the oesophagus with tylosis. Q. Jl Med. 39, 317.Google ScholarPubMed
Howel-Evans, A.W., McConnel, R.B., Clarke, C.A. & Sheppard, P.M. (1958) Carcinoma of the oesophagus with keratosis palmaris et plantaris (tylosis). Q. Jl Med. 27, 413.Google ScholarPubMed
Huriez, C., Deminatti, M., Aqache, P. & Mennecien, M. (1968) Une génodysplasie non encore individialisée. La génodermatome scléro-atrophiante et kératodermique des extrémiés frequemment dégénérative. Sem. Hôp. Paris, 44, 481.Google ScholarPubMed
Rook, A., Wilkinson, D.S. & Ebling, F.I. (1969) Textbook of Dermatology, Vol. 11, 2nd edn. Blackwell Scientific Publications, Oxford.Google Scholar
Samman, P.D. (1965) The Nails in Disease. Heinemann, London.Google Scholar
Scott, Q.L.S. (1953) Clinical Genetics, p. 210. Edited by Sorsby, A.. Butterworth London.Google Scholar
Sequira, J.H., Ingram, J.T. & Brain, R.J. (Eds) (1957) Diseases of the Skin, 6th edn, p. 39. Churchill, London.Google Scholar