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EFFECT OF INBREEDING ON WEIGHT GAIN OF OFFSPRING FROM BIRTH TO 12 MONTHS AFTER BIRTH: A STUDY FROM IRAN

Published online by Cambridge University Press:  26 October 2009

SAMANE NAFISSI ,
MARYAM ANSARI-LARI  and
MOSTAFA SAADAT
SAMANE NAFISSI
Affiliation:
Department of Biology, College of Sciences, Shiraz University, Iran
MARYAM ANSARI-LARI
Affiliation:
Department of Food Hygiene and Public Health, Shiraz University, Iran
MOSTAFA SAADAT
Affiliation:
Department of Biology, College of Sciences, Shiraz University, Iran
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Summary

Consanguinity, the marriage between relatives, has been associated with adverse child health outcomes. The objective of the present study was to assess the effect of consanguinity on offspring weight gain from birth to 12 months after birth. Data were collected on 250 consecutive live-born singleton newborns referred to a local health centre in Shiraz (Fars province, southern Iran). Collected data covered socio-demographic characteristics (such as parental age at delivery and parental education), sex, birth order, weights from birth to 12 months after birth and consanguinity of marriages of parents. Considering the low prevalence of double first cousin, first cousin once removed, second cousin, and beyond second cousin marriages, only first cousin and unrelated marriages were included in the study. The study population consisted of a total of 207 newborns (57 offspring of first cousins, 150 offspring of unrelated marriages). Based on the results of repeated measurements analysis of variance, weight gain was associated with type of marriage (p=0.018), sex of offspring (p=0.001) and paternal education (p<0.001). There was no interaction between type of marriage and sex (p=0.831). Birth weight was not affected by type of marriage (p=0.46). There was significant interaction between inbreeding and time (p=0.034). Offspring of consanguineous marriages showed lower weight gain in comparison with those of unrelated marriages during 3–12 months after birth.

Type
Research Article
Information
Journal of Biosocial Science , Volume 42 , Issue 2 , March 2010 , pp. 195 - 200
Copyright
Copyright © Cambridge University Press 2009

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