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On the time behaviour of Okazaki fragments

Part of: Mathematical biology in general Special processes Physiological, cellular and medical topics

Published online by Cambridge University Press:  14 July 2016

Krzysztof Bartoszek  and
Wojciech Bartoszek
Krzysztof Bartoszek*
Affiliation:
Gdańsk University of Technology
Wojciech Bartoszek*
Affiliation:
Gdańsk University of Technology
*
∗Postal address: Department of Mathematics, Gdańsk University of Technology, ul. Narutowicza 11/12, 80-952 Gdańsk Wrzeszcz, Poland.
∗Postal address: Department of Mathematics, Gdańsk University of Technology, ul. Narutowicza 11/12, 80-952 Gdańsk Wrzeszcz, Poland.
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Abstract

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We find explicit analytical formulae for the time dependence of the probability of the number of Okazaki fragments produced during the process of DNA replication. This extends a result of Cowan on the asymptotic probability distribution of these fragments.

Keywords

DNA replicationquasi-renewal equationOkazaki fragment

MSC classification

Primary: 60K05: Renewal theory
Secondary: 92B05: General biology and biomathematics 92C45: Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.)
Type
Research Papers
Information
Journal of Applied Probability , Volume 43 , Issue 2 , June 2006 , pp. 500 - 509
Copyright
© Applied Probability Trust 2006 

References

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