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Duality and Asymptotics for a Class of Nonneutral Discrete Moran Models

Published online by Cambridge University Press:  14 July 2016

Thierry Huillet*
Affiliation:
Université de Cergy-Pontoise
Martin Möhle*
Affiliation:
Eberhard Karls Universität Tübingen
*
Postal address: Laboratoire de Physique Théorique et Modélisation, CNRS-UMR 8098 et Université de Cergy-Pontoise, 2 Avenue Adolphe Chauvin, 95302 Cergy-Pontoise, France. Email address: [email protected]
∗∗Postal address: Mathematisches Institut, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 10, 72076 Tübingen, Germany. Email address: [email protected]
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Abstract

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A Markov chain X with finite state space {0,…,N} and tridiagonal transition matrix is considered, where transitions from i to i-1 occur with probability (i/N)(1-p(i/N)) and transitions from i to i+1 occur with probability (1-i/N)p(i/N). Here p:[0,1]→[0,1] is a given function. It is shown that if p is continuous with p(x)≤p(1) for all x∈[0,1] then, for each N, a dual process Y to X (with respect to a specific duality function) exists if and only if 1-p is completely monotone with p(0)=0. A probabilistic interpretation of Y in terms of an ancestral process of a mixed multitype Moran model with a random number of types is presented. It is shown that, under weak conditions on p, the process Y, properly time and space scaled, converges to an Ornstein–Uhlenbeck process as N tends to ∞. The asymptotics of the stationary distribution of Y is studied as N tends to ∞. Examples are presented involving selection mechanisms. results.

Type
Research Article
Copyright
Copyright © Applied Probability Trust 2009 

References

[1] Alkemper, R. and Hutzenthaler, M. (2007). Graphical representation of some duality relations in stochastic population models. Electron. Commun. Prob. 12, 206220.Google Scholar
[2] Athreya, S. R. and Swart, J. M. (2005). Branching-coalescing particle systems. Prob. Theory Relat. Fields 131, 376414.CrossRefGoogle Scholar
[3] Bender, E. A. (1973). Central and local limit theorems applied to asymptotic enumeration. J. Combinatorial Theory A 15, 91111.CrossRefGoogle Scholar
[4] Berg, C., Mateu, J. and Porcu, E. (2008). The Dagum family of isotropic correlation functions. Bernoulli 14, 11341149.CrossRefGoogle Scholar
[5] Bertoin, J. and Le Gall, J.-F. (2003). Stochastic flows associated to coalescent processes. Prob. Theory Relat. Fields 126, 261288.CrossRefGoogle Scholar
[6] Blythe, R. A. (2007). The propagation of a cultural or biological trait by neutral genetic drift in a subdivided population. Theoret. Pop. Biol. 71, 454472.Google Scholar
[7] Coop, C. and Griffiths, R. C. (2004). Ancestral inference on gene trees under selection. Theoret. Pop. Biol. 66, 219232.CrossRefGoogle ScholarPubMed
[8] Diaconis, P. and Fill, J. A. (1990). Strong stationary times via a new form of duality. Ann. Prob. 18, 14831522.Google Scholar
[9] Donnelly, P. (1984). The transient behavior of the Moran model in population genetics. Math. Proc. Camb. Phil. Soc. 95, 349358.Google Scholar
[10] Donnelly, P. (1985). Dual processes and an invariance result for exchangeable models in population genetics. J. Math. Biol. 23, 103118.Google Scholar
[11] Donnelly, P. (1986). Dual processes in population genetics. In Stochastic Spatial Processes (Lecture Notes Math. 1212), Springer, Berlin, pp. 94105.CrossRefGoogle Scholar
[12] Donnelly, P. and Rodrigues, E. R. (2000). Convergence to stationarity in the Moran model. J. Appl. Prob. 37, 705717.Google Scholar
[13] Ethier, S. N. and Krone, S. M. (1995). Comparing Fleming–Viot and Dawson–Watanabe processes. Stoch. Process. Appl. 60, 171190.Google Scholar
[14] Ethier, S. N. and Kurtz, T. G. (1986). Markov Processes. John Wiley, New York.CrossRefGoogle Scholar
[15] Ewens, W. J. (2004). Mathematical Population Genetics. I., 2nd edn. Springer, New York.CrossRefGoogle Scholar
[16] Feller, W. (1971). An Introduction to Probability Theory and Its Applications, Vol. II, 2nd edn. John Wiley, New York.Google Scholar
[17] Griffeath, D. (1993). Frank Spitzer's pioneering work on interacting particle systems. Ann. Prob. 21, 608621.Google Scholar
[18] Huillet, T. (2009). A duality approach to the genealogies of discrete non-neutral Wright–Fisher models. J. Prob. Statist. 2009, 714701, 22 pp.CrossRefGoogle Scholar
[19] Kämmerle, K. (1989). Looking forwards and backwards in a bisexual Moran model. J. Appl. Prob. 26, 880885.CrossRefGoogle Scholar
[20] Kingman, J. F. C. (1982). The coalescent. Stoch. Process. Appl. 13, 235248.CrossRefGoogle Scholar
[21] Liggett, T. M. (1985). Interacting Particles Systems. Springer, New York.Google Scholar
[22] Liggett, T. M. (1999). Stochastic Interacting Systems: Contact, Voter and Exclusion Processes. Springer, Berlin.Google Scholar
[23] Moran, P. A. P. (1958). Random processes in genetics. Proc. Camb. Phil. Soc. 54, 6071.Google Scholar
[24] Möhle, M. (1994). Forward and backward processes in bisexual models with fixed population sizes. J. Appl. Prob. 31, 309332.Google Scholar
[25] Möhle, M. (1999). The concept of duality and applications to Markov processes arising in neutral population genetics models. Bernoulli 5, 761777.CrossRefGoogle Scholar
[26] Möhle, M. (2001). Forward and backward diffusion approximations for haploid exchangeable population models. Stoch. Process. Appl. 95, 133149.Google Scholar
[27] Siegmund, D. (1976). The equivalence of absorbing and reflecting barrier problems for stochastically monotone Markov processes. Ann. Prob. 4, 914924.Google Scholar
[28] Spitzer, F. (1970). Interaction of Markov processes. Adv. Math. 5, 246290.CrossRefGoogle Scholar
[29] Sudbury, A. and Lloyd, P. (1995). Quantum operators in classical probability theory. II. The concept of duality in interacting particle systems. Ann. Prob. 23, 18161830.Google Scholar
[30] Wang, Y. and Yeh, Y.-N. (2007). Log-concavity and LC-positivity. J. Combinatorial Theory A 114, 195210.Google Scholar