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Androgen receptor (AR), estrogen receptor-alpha (ER-α) and estrogen receptor-beta (ER-β) expression in the testis of the newt, Triturus marmoratus marmoratus during the annual cycle

Published online by Cambridge University Press:  23 October 2001

M. I. ARENAS
Affiliation:
Department of Cell Biology and Genetics, University of Alcalá, Madrid, Spain
M. ROYUELA
Affiliation:
Department of Cell Biology and Genetics, University of Alcalá, Madrid, Spain
M. V. T. LOBO
Affiliation:
Department of Cell Biology and Genetics, University of Alcalá, Madrid, Spain
J. M. ALFARO
Affiliation:
Department of Cell Biology and Genetics, University of Alcalá, Madrid, Spain
B. FRAILE
Affiliation:
Department of Cell Biology and Genetics, University of Alcalá, Madrid, Spain
R. PANIAGUA
Affiliation:
Department of Cell Biology and Genetics, University of Alcalá, Madrid, Spain
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Abstract

Expression of androgen receptor (AR), estrogen receptor alpha (ER-α) and estrogen receptor beta (ER-β) in the testis of the marbled newt (Triturus marmoratus marmoratus) was investigated, with special attention to changes during the annual testicular cycle, using light microscopy immunohistochemistry and Western blot analysis. Primordial germ cells, primary and secondary spermatogonia and spermatocytes showed a positive reaction to the 3 receptor antibodies during the annual reproductive cycle. Follicular cells were positive to AR, ER-α and ER-β during the spermiogenesis and quiescence periods in the glandular tissue. Interstitial cells showed reactivity to AR, ER-α and ER-β in the spermiogenesis and the quiescence periods, and presented no labelling to these receptors in the proliferative period. These findings suggest that, as in mammals, there is an androgen-estrogen regulation of the function and development of the newt testis.

Type
Papers
Copyright
© Anatomical Society of Great Britain and Ireland 2001

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