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Review. Articular cartilage chondrons: form, function and failure

Published online by Cambridge University Press:  01 July 1997

C. ANTHONY POOLE
C. ANTHONY POOLE
Affiliation:
Department of Anatomy, Faculty of Medicine and Health Science, University of Auckland, Auckland, New Zealand
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Abstract

The chondrocyte and its pericellular microenvironment together represent the chondron, historically considered the primary structural, functional and metabolic unit of articular and other hyaline cartilages. This review summarises research over the last 10 years to establish the molecular anatomy, functional properties and metabolic contribution of the chondron in articular cartilage homeostasis, and its failure during the initiation and progression of degenerative osteoarthritis.

Keywords

Articular cartilagechondronschondrocytespericellular microenvironmentosteoarthritis
Type
Review Article
Information
The Journal of Anatomy , Volume 191 , Issue 1 , July 1997 , pp. 1 - 13
Copyright
© Anatomical Society of Great Britain and Ireland 1997

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