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The response of key gluconeogenic enzymes in bovine liver to various dietary and hormonal regimes

Published online by Cambridge University Press:  27 March 2009

G. D. Baird  and
Janice L. Young
G. D. Baird
Affiliation:
Biochemistry Department, Agricultural Research Council, Institute for Research on Animal Diseases, Compton, Berks
Janice L. Young
Affiliation:
Biochemistry Department, Agricultural Research Council, Institute for Research on Animal Diseases, Compton, Berks
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Summary

The effects of starvation, glucocorticoid administration, and the feeding of an all-concentrate diet, on the 14CO2-fixing activities of pyruvate carboxylase (EC. 6.4.1.1), phosphopyruvate carboxylase (EC. 4.1.1.32) and propiony1-CoA carboxylase (EC. 6.4.1.3) were measured in liver from lactating cows. Starvation caused a 26% decrease in propiony1-CoA carboxylase activity, glucocorticoid administration a 35% decrease in phosphopyruvate carboxylase activity, and the all-concentrate diet 24 and 41% increases in the activities of phosphopyruvate carboxylase and propiony1-CoA carboxylase respectively.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 84 , Issue 2 , April 1975 , pp. 227 - 230
Copyright
Copyright © Cambridge University Press 1975

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References

REFERENCES

Baird, G. D. & Heitzman, R. J. (1970). Gluconeogenesis in the cow. The effects of a glucocorticoid on hepatic intermediary metabolism. Biochemical Journal 116, 865–74.CrossRefGoogle ScholarPubMed
Baird, G. D. & Heitzman, R. J. (1971). Mode of action of a glucocorticoid on bovine intermediary metabolism. Possible role in controlling hepatic ketogenesis. Biochimica et Biophysica Acta 252, 184–98.CrossRefGoogle ScholarPubMed
Baird, G. D., Heitzman, R. J. & Hibbitt, K. G. (1972). Effects of starvation on intermediary metabolism in the lactating cow. A comparison with metabolic changes occurring during bovine ketosis. Biochemical Journal 128, 1311–18.CrossRefGoogle ScholarPubMed
Baird, G. D., Hibbitt, K. G., Hunter, G. D., Lund, P., Stubbs, M. & Krebs, H. A. (1968). Biochemical aspects of bovine ketosis. Biochemical Journal 107, 683–9.CrossRefGoogle ScholarPubMed
Ballard, F. J. & Hanson, R. W. (1967). Phosphoenolpyruvate carboxykinase and pyruvate carboxylase in developing rat liver. Biochemical Journal 104, 866–71.CrossRefGoogle ScholarPubMed
Bergman, E. N. (1973). Glucose metabolism in ruminants as related to hypoglycemia and ketosis. Cornell Veterinarian 63, 341–82.Google Scholar
Kazibo, Y. (1969). Crystalline propiony1-CoA carboxylase from pig heart. In Methods in Enzymology, vol. 13 (ed. Lowenstein, J. M.), pp. 181–90. New York and London: Academic Press.Google Scholar
Krebs, H. A. (1966). Bovine ketosis. Veterinary Record 78, 187–92.CrossRefGoogle ScholarPubMed
Lane, M. D., Chang, H. C. & Miller, R. S. (1969). Phosphoenolpyruvate carboxykinase from pig liver mitochondria. In Methods in Enzymology, vol. 13 (ed. Lowenstein, J. M.), pp. 270–77. New York and London: Academic Press.Google Scholar
Lindsay, D. B. (1970). Carbohydrate metabolism in the ruminant. In Physiology of Digestion and Metabolism in the Ruminant (ed. Phillipson, A. T.), pp. 438–51. Newcastle-upon-Tyne: Oriel Press.Google Scholar
Williamson, D. H., Mayor, F. & Veloso, D. (1971). Effects of quinolinic acid on the free and total nicotinamideadenine dinucleotides of rat liver. In Regulation of Gluconeogenesis (ed. Söling, H.-D. and Willms, B.), pp. 92–102. New York and London: Academic Press.CrossRefGoogle Scholar