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The influence of chemical constitution on the toxicity of organic compounds to wireworms

Published online by Cambridge University Press:  27 March 2009

F. Tattersfield  and
A. W. R. Roberts
F. Tattersfield
Affiliation:
(Rothamsted Experimental Station).
A. W. R. Roberts
Affiliation:
(Rothamsted Experimental Station).
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Extract

1. The relationship between chemical constitution and toxicity to wireworms of organic compounds is found to be of a twofold nature.

2. The general effect of a group of compounds of the same type is directly determined by the chemical constitution of the type. The particular effects of individual members of the groups are limited by their physical properties such as volatility etc., which may be regarded as indirect consequences of their chemical constitution.

3. The aromatic hydrocarbons and halides are on the whole more toxic than the aliphatic hydrocarbons and halides. The groups that influence toxicity most when introduced singly into the benzene ring are in order of importance the methylamido (most effective), dimethylamido, hydroxy, nitro, amido, iodine, bromine, chlorine, methyl groups (least effective). But this order is modified in presence of another group; thus when there is a CH3 already present in the ring the order becomes chlorine (side chain), amido, hydroxy, chlorine (ring), methyl. Chlorine and hydroxy groups together give rise to highly poisonous substances considerably more effective than where present separately. The association of chlorine and nitro groups in chloropicrin gives rise to one of the most toxic substances tested. Methyl groups substituted in the amido group of aniline increase toxicity more than if substituted in the ring.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 10 , Issue 2 , April 1920 , pp. 199 - 232
Copyright
Copyright © Cambridge University Press 1920

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References

LITERATURE CITED

(1)Holt, J. J. H.The Cockroach; its destruction and dispersal. Lancet, 1916, 5, 190, p. 1136.CrossRefGoogle Scholar
(2)Moore, W.The Toxicity of various Benzene Derivatives to Insects. J. Agric. Research, 1917, 9, p. 371.Google Scholar
(3)Moore, W.Volatility of Organic Compounds as an Index of the Toxicity of their Vapours to Insects. J. Agric. Research, 1917, 10, p. 365.Google Scholar
(4)Moore, W. and Graham, S. A.A study of the Toxicity of Kerosene. J. Economic Entomology, 1918, 11, p. 70.Google Scholar
(5)Moore, Wm.Physical Properties governing Contact Insecticides. J. Agric. Research, 1918, 13, p. 523.Google Scholar
(6)Brown, H. T. The Principles of Diffusion, their Analogies and Applications. Journ. Chem. Soc. 1918, Trans. 559.CrossRefGoogle Scholar
(7)Shafer, G. D.How Contact Insecticides kill. Michigan Board of Agriculture Expt. Station Bulletins. Technical Bull. No. 11, 1912, p. 536; No. 21, 1916, p. 435.Google Scholar
(8)Gibbs, H. D.Compounds which cause the Red Coloration of Aniline. Journ. Chem. Soc. 1910, A. 1, 550. Philippine J. Sci. 1910, 5, 9–16. Journ. Chem. Soc. 1911, A. 1, 534. Philippine J. Sci. 1910, 5, 419–435.Google Scholar
(9)Cooper, E. A.The Chemical Action of Quinones upon Proteins. Biochemical J. 1913, 7, p. 186.Google Scholar
(10)Cooper, E. A.The Germicidal and Protein Precipitating Powers of Phenols. Biochemical J. 1913, 7, p. 175.Google Scholar
(11)Rapp, . Disinfectant Value of the Three Isomeric Cresols. Journ. Chem. Soc. 1907, A. 2, 982. Chem. Centr. 1907, 2, 717.Google Scholar
(12)Bechhold, H. and Ehrlich, P.Relationship between Chemical Constitution and Disinfectant Properties. Journ. Chem. Soc. 1906, A. 2, 383. Zeit. physiol. Chem. 1906, 47, 173–199.Google Scholar
(13)Foreman, F. W. and Graham Smith, G. S.Investigations on the Prevention of Nuisances arising from Flies and Putrefaction. J. of Hygiene, 1917, 16, No. 2, p. 114.Google Scholar
(14)Bokorny, Th.Pflüger's Archiv für Physiologie, 1896, 64, p. 262. Centralblatt für Bacteriologie, 1913, Bd. 37, p. 168.Google Scholar
(15)Morgan, G. I. and Cooper, E. A.The Influence of the Chemical Constitution of certain organic hydroxyl and aminic derivatives on their Germicidal Power. 8th Int. Congress of Applied Chem. 1912, 19, p. 243.Google Scholar