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Effects of pregnancy and lactation on the activities in sheep liver of some enzymes of glucose metabolism

Published online by Cambridge University Press:  27 March 2009

R. W. Smith  and
Ann Walsh
R. W. Smith
Affiliation:
National Institute for Research in Dairying, Shinfield, Reading, RG2 9AT
Ann Walsh
Affiliation:
National Institute for Research in Dairying, Shinfield, Reading, RG2 9AT
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Summary

The activities of some enzymes that regulate the gluconeogenic-glycolytic pathway were measured in sheep liver during late pregnancy, at three stages of lactation and after the lambs were weaned. Of the gluconeogenic enzymes, glucose-6-phosphatase and phosphoenolpyruvate carboxylase activities were unchanged throughout pregnancy and lactation and were similar to the values for non-breeding ewes. The activity of fructose diphosphatase increased 2 times and that of pyruvate carboxylase increased 5–7 times during late pregnancy and in early lactation.

In the glycolytic sequence phosphofructokinase activity declined by about 50% during lactation. Pyruvate kinase activity declined by about 40% at the end of pregnancy but throughout lactation it was similar to the value for non-breeding ewes. Hexokinase activity was very low in all animals.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 98 , Issue 3 , June 1982 , pp. 563 - 565
Copyright
Copyright © Cambridge University Press 1982

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References

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