Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-25T03:58:31.288Z Has data issue: false hasContentIssue false
  • English
  • Français

Effect of disease on the oestrogenic activity and coumestrol content of white clover and lucerne

Published online by Cambridge University Press:  27 March 2009

N. Saba ,
Hilary M. Drane ,
C. Nancy Hebert ,
J. E. Newton  and
J. E. Betts
N. Saba
Affiliation:
Central Veterinary Laboratory, Ministry of Agriculture, Fisheries and Food, Weybridge, Surrey
J. E. Newton
Affiliation:
Grasslands Besearch Institute, Hurley, Berkshire
J. E. Betts
Affiliation:
Grasslands Besearch Institute, Hurley, Berkshire
Get access Rights & Permissions [Opens in a new window]

Summary

The oestrogenic activity and coumestrol content of ‘diseased’ and ‘clean’ white clover and lucerne were investigated. It was found that both coumestrol content and oestrogenic activity were increased in diseased white clover. However, there was insufficient coumestrol to account for the oestrogenic activity and it was suggested that other factors (e. g. oestrogen potentiator, unidentified oestrogen) were involved.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 78 , Issue 3 , June 1972 , pp. 471 - 475
Copyright
Copyright © Cambridge University Press 1972

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Bennetts, H. W., Underwood, E. J. & Shier, F.s L. (1946). A specific breeding problem of sheep on subterranean clover pastures in Western Australia. Aust. vet. J. 22, 2–12.CrossRefGoogle ScholarPubMed
Bickoff, E. M. (1968). Oestrogenic constituents of forage plants. Commonwealth Agricultural Bureau, Review Series no. 1/1968.Google Scholar
Bickoff, E. M., Booth, A. N., Lyman, R. L., Livingstone, A. L., Thompson, C. R. & De Eds, F. (1957). Coumestrol, a new estrogen isolated from forage crops. Science, N. Y. 126, 969–70.CrossRefGoogle ScholarPubMed
Bickoff, E. M., Booth, A. N., Livingstone, A. L. & Hendrickson, A. P. (1960 a). Observations on the effects of drying on estrogenic activity of alfalfa samples of varying maturity. J. Anim. Sci. 19, 745–53.CrossRefGoogle Scholar
Bickoff, E. M., Livingstone, A. L., Booth, A. N., Thompson, C. R., Hollowell, E. A. & Beinhakt, E. G. (1960 b). Some variation in estrogenic activity in fresh and dried white clover clones and the ladino variety. J. Anim. Sci. 19, 1143–9.CrossRefGoogle Scholar
Bickoff, E. M., Livingstone, A. L., Booth, A. N., Hendrickson, A. P. & Kohler, G. O. (1960 C). Estrogenic activity in dehydrated and suncured forages. J. Anim. Sci. 19, 189–97.CrossRefGoogle Scholar
Bickoff, E. M., Loper, G. M., Hanson, C. H., Graham, J. H., Witt, S. C. & Spencer, R. R. (1967). Effect of common leafspot on coumestans and flavones in alfalfa. Crop Sci. 7, 259–61.CrossRefGoogle Scholar
Drane, H. M. & Saba, N. (1968). Oestrogenic activity in legumes. J. agric. Sci., Camb. 70, 165–7.CrossRefGoogle Scholar
Engle, P. H., Bell, D. S. & Davis, R. R. (1957). The effect of ladino clover, birdsfoot trefoil and bluegrass pasture on the rate of conception among ewes. J. Anim. Sci. 16, 703–10.CrossRefGoogle Scholar
Guggolz, J., Livingstone, A. L. & Bickoff, E. M. (1961). Detection of daidzein, formononetin, genisteine and biochanin A in forages. J. agric. Fd Chem. 9, 330–2.CrossRefGoogle Scholar
Livingstone, A. L., Bickoff, E. M., Guggolz, J. & Thompson, C. R. (1961). Quantitative determination of coumestrol in fresh and dried alfalfa. J. agric. Fd Chem. 9, 135–7.CrossRefGoogle Scholar
Loper, G. M. & Hanson, C. H. (1964). Influence of controlled environmental factors and two foliar pathogens on coumestrol in alfalfa. Crop Sci. 4, 480–2.Google Scholar
Martin, L. (1964). Further studies on the use of tetrazolium in the biological assay of oestrogens. J. Endocr. 30, 21–31.CrossRefGoogle ScholarPubMed
Moule, G. R., Braden, A. W. H. & Lamond, D. R. (1963). The significance of oestrogens in pasture plants in relation to animal production. Anim. Breed. Abstr. 31, 139–57.Google Scholar
Newton, J. E. & Betts, J. E. (1968). Seasonal oestrogenic activity of various legumes. J. agric. Sci., Camb. 70, 77–82.CrossRefGoogle Scholar
Pieterse, P. J. S. & Andrews, F. N. (1956). The estrogenic activity of alfalfa and other foodstuffs. J. Anim. Sci. 15, 25–36.CrossRefGoogle Scholar
Pope, G. S. (1954). The importance of pasture plant oestrogens in the reproduction and lactation of grazing animals. Dairy Sci. Abstr. 16, 334–55.Google Scholar
Pope, G. S., Mc Naughton, M. J. & Jones, H. E. (1959). Oestrogens in British pasture plants. J. Dairy Bes. 26, 196–202.CrossRefGoogle Scholar
Shemesh, M., Lindner, H. R. & Ayalon, N. (1969). Coumestrol and 4'-0-methylcoumestrol in alfalfa grown in northern Israel. Possible effect of a foliar pathogen (Pseudopeziza medicaginis(Lib.)). Refuahvet. 26, 1–7.Google Scholar