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Computer simulation of bovine copper metabolism

Published online by Cambridge University Press:  27 March 2009

C. Blincoe
C. Blincoe
Affiliation:
University of Nevada, Reno, NV 89557, USA
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Summary

Copper deficiency in cattle is a world-wide problem. A deterministic digital computer simulation of copper metabolism was applied to cattle and especially to their response to dietary copper. This simulation was verified by comparison with published data on copper metabolism of cattle. Copper loss under conditions of dietary deficiency was governed largely by the rate of hepatic loss of copper. Copper stores were replenished gradually when the animal was returned to a normal diet. The increased copper consumption associated with increased total digestible nutrients (TDN) during lactation compensated for loss of copper in milk. Cattle have a very efficient mechanism for extrahepatic copper homeostasis by storage of excess copper in the liver, which can then be withdrawn in future deficiencies.

Type
Animals
Information
The Journal of Agricultural Science , Volume 121 , Issue 1 , August 1993 , pp. 91 - 96
Copyright
Copyright © Cambridge University Press 1993

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