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Activity of cytoplasmic acetyl-CoA hydrolase in sheep liver and its potential role in heat production

Published online by Cambridge University Press:  27 March 2009

N. S. Jessop ,
N. D. Scollan ,
M. J. Souter  and
B. Crabtree
N. S. Jessop
Affiliation:
Department of Agriculture, University of Edinburgh, King's Buildings, West Mains Road, Edinburgh EH9 3JGUK
N. D. Scollan
Affiliation:
Department of Agriculture, University of Edinburgh, King's Buildings, West Mains Road, Edinburgh EH9 3JGUK
M. J. Souter
Affiliation:
The Rowett Research Institute, Bucksburn, Aberdeen AB2 9SBUK
B. Crabtree
Affiliation:
The Rowett Research Institute, Bucksburn, Aberdeen AB2 9SBUK
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Summary

Acetyl-CoA hydrolase which is stimulated by adenosine-5′-triphosphate is present in the cytoplasm of ovine liver and, unlike in certain others species, is not inactivated by cold. It is suggested that this enzyme is involved in a substrate cycle between acetate and acetyl-CoA. The heat produced as a result of such cycling may be as much as 2·5% of basal heat production and may be partly responsible for the increased heat increment that often follows the ingestion of diets that provide large quantities of acetate.

Type
Animals
Information
The Journal of Agricultural Science , Volume 115 , Issue 2 , October 1990 , pp. 265 - 267
Copyright
Copyright © Cambridge University Press 1990

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References

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