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The absorption of subcutaneously implanted thyroxine in the sheep

Published online by Cambridge University Press:  27 March 2009

D. Lewis
D. Lewis
Affiliation:
A.R.C. Institute of Animal Physiology, Babraham, Cambridge, andUniversity of Nottingham School of Agriculture, Sutton Bonington, near Loughborough
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Extract

1. Pellets of L-thyroxine (30 mg.) were implanted subcutaneously in sheep. The loss in weight of the implants and the plasma P.b.i. level were determined at intervals.

2. The P.b.i. concentration increased within a few days from a normal value of around 5 μg./100 ml. to one of 15–20 μg./100 ml. After 10–20 days the concentration slowly returned to normal, and at 70 days subsequent to implantation was only slightly above the normal level.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 56 , Issue 1 , February 1961 , pp. 65 - 67
Copyright
Copyright © Cambridge University Press 1961

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References

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