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Sodium transport by lamb proximal colon measured during early postnatal development

Published online by Cambridge University Press:  27 March 2009

M. W. Smith  and
P. S. James
M. W. Smith
Affiliation:
Agricultural Research Council Institute of Animal Physiology, Babraham, Cambridge, CB2 4AT
P. S. James
Affiliation:
Agricultural Research Council Institute of Animal Physiology, Babraham, Cambridge, CB2 4AT
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Summary

Proximal colons taken from lambs up to 3 weeks after birth were shown to transport both sodium and chloride from lumen to blood when incubated in vitro.

Sodium transport fell into three phases during postnatal development. The first covered the period from birth to 3 days of age when sodium transport was high and equal to that calculated from measurement of short-circuit current. The second was seen in 5- and 7-day-old lambs where the short-circuit current was low and the net transport of sodium was negligible. The third was seen in 2-3-week-old lambs where sodium transport was high, but the short-circuit current was low.

Chloride absorption by colons taken from 1-day-old lambs appeared to be in exchange for an anion, possibly bicarbonate. Chloride absorption by colons taken from 3-week-old lambs appeared to be electrogenie or coupled directly to the transport of sodium.

A possible explanation for the failure of electrolyte absorption by colons taken from 5- and 7-day-old lambs is discussed.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 98 , Issue 1 , February 1982 , pp. 155 - 159
Copyright
Copyright © Cambridge University Press 1982

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References

REFERENCES

Bentley, P. J. & Smith, M. W. (1975). Transport of electrolytes across the helicoidal colon of the newborn pig. Journal of Physiology 249, 103–117.CrossRefGoogle Scholar
Cremaschi, D., Ferguson, D. R., Hénin, S., James, P. S., Meyer, G. & Smith, M. W. (1979). Post-natal development of amiloride sensitive sodium transport in pig distal colon. Journal of Physiology 292, 481–494.CrossRefGoogle ScholarPubMed
Cremaschi, D., James, P. S., Meyer, G. & Smith, M. W. (1981). Electrophysiology of pig distal colon measured during early post-natal development. Journal of Physiology 314, 137–149.CrossRefGoogle ScholarPubMed
Frizzell, R. A., Dugas, M. C. & Schultz, S. G. (1975). Sodium chloride transport by rabbit gallbladder: direct evidence for a coupled NaCl influx process. Journal of General Physiology 65, 769–795.CrossRefGoogle ScholarPubMed
Frizzell, R. A., Koch, M. J. & Schultz, S. G. (1976). Ion transport by rabbit colon. I. Active and passive components. Journal of Membrane Biology 27, 297–316.CrossRefGoogle Scholar
Henkiques de Jesus, C. & Smith, M. W. (1974). Sodium transport by the small intestine of new-born and suckling pigs. Journal of Physiology 243, 211–224.CrossRefGoogle Scholar
Hills, F., James, P. S., Paterson, J. Y. F. & Smith, M. W. (1980). Delayed development of amiloridesensitive sodium transport in lamb distal colon. Journal of Physiology 303, 371–384.CrossRefGoogle ScholarPubMed
Krebs, H. A. & Henseleit, K. (1932). Untersuchungen über die Harnstoffbildung im Tierkörper. Hoppe Seyler's Zeitschrift für physiologische Chemie 210, 33–66.CrossRefGoogle Scholar
Smith, M. W. & James, P. S. (1979). Absorption of methionine by foetal and neonatal lamb colon. Journal of Agricultural Science, Cambridge 92, 39–43.CrossRefGoogle Scholar
Smith, M. W. & James, P. S. (1982). Absorption of glucose by lamb proximal colon measured during early postnatal development. Journal of Agricultural Science, Cambridge 98, 161–165.CrossRefGoogle Scholar
Stanier, M. W. (1972). Development of intra-renal solute gradients in foetal and postnatal life. Pflügers Archives 336, 263–270.CrossRefGoogle Scholar