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Effect of dose of Gronolone in intravaginal sponges on lambing outcome to fixed-time artificial insemination
Published online by Cambridge University Press: 27 March 2009
Extract
Research has shown that it is now possible to control the oestrous cycle of ewes with a high degree of precision (Robinson et al. 1967; Gordon, 1975; Boland, Kelleher & Gordon, 1978). There is general agreement that a high concentration of progestagen, followed by rapid withdrawal and adequate ovarian stimulation is necessary for acceptable fertility (Robinson et al. 1967; Gordon, 1975; Colas, 1975). Application of artificial insemination in France has involved the use of a 40–45 mg Cronolone sponge (Cognie, Mariana & Thimonier, 1970; Colas et al. 1973) while controlled breeding in sheep in Ireland has been used in conjunction with a 30 mg Cronolone pessary (Gordon, 1975; Smith, Boland & Gordon, 1978, 1981). The present experiment was designed to compare the relative effectiveness of two doses of Cronolone (30 or 45 mg) when administered in conjunction with two quantities(375 or 750 i.u.) of pregnant mare serum gonadotrophin (PMSG), given by intramuscular injection.
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