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Wilson's disease and the neuroleptic malignant syndrome

Published online by Cambridge University Press:  13 June 2014

Peter Buckley ,
Eamonn Carmody  and
Michael Hutchinson
Peter Buckley*
Affiliation:
Cluain Mhuire Family Centre, Blackrock, Co. Dublin
Eamonn Carmody
Affiliation:
Beaumont Hospital, Dublin
Michael Hutchinson
Affiliation:
St. Vincent's Hospital, Dublin
*
Cluain Mhuire Family Centre, Newtownpark Avenue, Blackrock, Co.Dublin
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Abstract

Wilson's Disease (Hepatolenticular degeneration) is an uncommon disorder of copper metabolism, characterised by excessive copper deposition in the liver, brain and eyes. Psychiatric symptoms were prominent in eight of the twelve patients originally described by Wilson some 88 years ago. Since then a wide range of psychiatric presentations have been documented including behavioural disturbances, affective psychoses, schizophrenia-like psychoses, intellectual deterioration and dementia. Here we describe a patient who presented with a psychiatric disturbance, was treated with neuroleptic medication and subsequently developed Neuroleptic Malignant Syndrome (NMS).

Keywords

Hepatolenticular degenerationNeuroleptic Malignant Syndrome.
Type
Clinical and Brief Reports
Information
Irish Journal of Psychological Medicine , Volume 7 , Issue 2 , September 1990 , pp. 138 - 139
Copyright
Copyright © Cambridge University Press 1990

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