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Thomas Willis (1621-1675): First lines in Neuropsychiatry

Published online by Cambridge University Press:  13 June 2014

Caoimhghin Breathnach*
Affiliation:
Dept of Human Anatomy and Physiology, University College Dublin, Earlsfort Terrace, Dublin 2, Ireland

Abstract

Thomas Willis [1621-1675] was not the first to describe the circle of vessels at the base of the brain that bears his name, but it was he who first recognised its functional significance in maintaining cerebral perfusion even after one of its feeding vessels was completely closed. Although Willis made many astute, original clinical observations (concerning myasthenia gravis, paracusis, restless legs syndrome and diabetes mellitus) his reputation suffered because he was an inveterate theorist in an age that frowned on hypotheses. Nonetheless he is now recognised as one of the earliest neuropsychiatrists who attempted to understand and explain mental illness, as he encountered it in his daily practice, in terms of brain dysfunction more than 300 years ago.

Type
Historical
Copyright
Copyright © Cambridge University Press 1996

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References

1.Aubrey, J. Brief, lives. ed. Oliver Lawson Dick. London. Penguin. 1949. Reprinted Penguin Classics. 1987.Google Scholar
2.Trevor, Hughes J. Thomas Willis 1621-1675. His Life and Work. London. Royal Society of Medicine Services Ltd. 1991.Google Scholar
3.Dewhurst, K. Willis's Oxford Lectures. Oxford. Sandford Publications. 1980.Google Scholar
4.Frank, RG. Harvey and the Oxford physiologists. Berkeley. University of California Press. 1980.Google Scholar
5.Parker, S. An account of the nature and content of the Divine dominion and goodnesse. Oxford 1667, cited by Prank (reference 4 p. 183).Google Scholar
6.Lutz, EG. Restless legs, anxiety and caffeine. Journal of Clinical Psychiatry 1978; 39: 693698.Google Scholar
7.Drury, MI. The pissing evil. Irish Journal of Medical Science 1985; 154: 113.CrossRefGoogle Scholar
8.Frank, RG. Thomas Willis and his circle: brain and mind in seventeenth-century medicine. in The languages of Psyche: mind and body in Enlightenment thought. Edited by Rousseau, GS. Berkeley: University of California Press 1990.Google Scholar
9.Conry, Y. Willis, Thomas. ou le premier discours rationaliste en pathologie mentale. L'Information Psychiatrique 1982: 58: 313323.Google Scholar
10.Sherrington, CS. Man on his nature. Cambridge. Cambridge University Press. 1951. Second edition.Google Scholar
11.Berrios, EG. Dementia during the seventeenth and eighteenth centuries. Psych Med 1987; 17: 829837.CrossRefGoogle ScholarPubMed
12.Vinchon, J. Vie, J. Un maitre de la neuropsychiatrie au XVIIe siecle: Thomas Willis (1662-1675). Annales medico Psychologique l928; 86: 109144.Google Scholar