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Schizophrenia and Down's syndrome

Published online by Cambridge University Press:  13 June 2014

Chandrudu Duggirala ,
Sally-Ann Cooper  and
Richard Anthony Collacott
Chandrudu Duggirala
Affiliation:
Frith Hospital, Leicester, England
Sally-Ann Cooper
Affiliation:
St Mary's Hospital, Kettering, England
Richard Anthony Collacott
Affiliation:
Department of Psychiatry, University of Leicester, Leicester, England
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Abstract

There are few reports in the literature of schizophrenia in individuals with Down's syndrome, but a suggestion that such individuals may be protected from schizophrenia. We report six cases of schizophrenia fulfilling ICD-10 guidelines, occurring in people with Down's syndrome. In one case, hypothyroidism was associated. Response to neuroleptic treatment was good. Reasons for the paucity of previous reports on this association are discussed.

Keywords

SchizophreniaDown's syndromeMental retardation
Type
Brief Reports
Information
Irish Journal of Psychological Medicine , Volume 12 , Issue 1 , March 1995 , pp. 30 - 33
Copyright
Copyright © Cambridge University Press 1995

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