Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-05T01:06:35.222Z Has data issue: false hasContentIssue false
  • English
  • Français

Recurrent transient parotid gland swelling with clozapine therapy

Published online by Cambridge University Press:  13 June 2014

Natarajan Kathirvel ,
Shajahan Ismail  and
Sean A Spence
Natarajan Kathirvel
Affiliation:
Fitzwilliam Centre, Sheffield, UK
Shajahan Ismail
Affiliation:
Michael Carlisle Centre, Sheffield, UK
Sean A Spence
Affiliation:
Academic Clinical Psychiatry, University of Sheffield, UK
Get access Rights & Permissions [Opens in a new window]

Abstract

We report a case of recurrent parotid gland swelling in a man receiving clozapine. Our aim is to raise awareness of this iatrogenic condition and to review what is known of its pathogenesis and management.

Type
Case Reports
Information
Irish Journal of Psychological Medicine , Volume 25 , Issue 2 , June 2008 , pp. 69 - 70
Copyright
Copyright © Cambridge University Press 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Hippius, H. A historical perspective on clozapine. J Clin Psychiat 1999; 60 (Suppl 12): 22–23.Google ScholarPubMed
2.Kane, J, Honigfeld, G, Singer, J, Meltzer, H. Clozapine for the treatment-resistant schizophrenic: a double-blind comparison with chlorpromazine. Archives of General Psychiatry 1988; 45; 789–96.CrossRefGoogle ScholarPubMed
3.Lieberman, JAet al.Clinical effects of clozapine in chronic schizophrenia; response to treatment and predictors of outcome. Amer J Psychiat 1994; 151:1744–52.Google ScholarPubMed
4.Buckley, FP, Waddington, U. Schizophrenia and Mood Disorders: the new drug therapies in clinical practice (1st ed). London: Arnold Publishers. 2003.Google Scholar
5.Cookson, J, Taylor, D, Katona, CUse of drugs in psychiatry (5th ed). London: Gaskell. 2002.Google Scholar
6.World Health Organisation. The ICD-10 Classification of Mental and Behavioural Disorders. Geneva. 1992.Google Scholar
7.Ledingham, GGJ, Warrel, AD. Concise Oxford Textbook of Medicine. Oxford: Oxford University Press. 2000.Google Scholar
8.Robinson, D, Fenn, H, Yesavage, J. Possible association of parotitis and clozapine. American Journal of Psychiatry 1995; 152: 297–298.Google ScholarPubMed
9.Troia, M, Berardi, D, Sanza, M, Dell'Atti, M, Ferrari, G. Swelling of salivary glands with clozapine treatment. Canadian Journal of Psychiatry 1996; 41: 485–6.CrossRefGoogle ScholarPubMed
10.Cree, A, Mir, S, Fahy, T. A review of the treatment options for clozapine-induced hypersalivation. Psychiatric Bulletin 2001; 25:114–6.CrossRefGoogle Scholar
11.Vasile, SJ, Steingard, S. Clozapine and the development of salivary gland swelling: A Case Study. J Clin Psychiat 1995; 56:113–3.Google ScholarPubMed
12.Hinze-Selch, D, Becker, WE, Stein, G, Schreiber, W, Pollmacher, T, Clozapine-induced parotitis: An immunological cause? American Journal of Psychiatry 1996; 153: 840.Google ScholarPubMed
13.Brodkin, SE, Pelton, HG, Price, HL. Treatment of clozapine-induced parotid gland swelling. Amer J Psychiat 1996; 153: 445–6.Google ScholarPubMed
14.Southall, K, Fernando, N. Report of a rare medical complication of clozapine. The Australian and New Zealand J Psychiat 1999; 33:122–3.Google ScholarPubMed