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Familial dementia with Pick's cells – a case report of probable familial Pick's disease

Published online by Cambridge University Press:  13 June 2014

Fiona Gaughran ,
Catherine Keohane  and
Mary Buckley
Fiona Gaughran
Affiliation:
Dept of Psychiatry, St Stephen's Hospital, Glanmire, Co. Cork, Ireland
Catherine Keohane
Affiliation:
Neuropathology Laboratory, Dept of Pathology, Cork Regional Hospital, Wilton, Cork, Co. Cork, Ireland
Mary Buckley
Affiliation:
Dept of Psychiatry, St. Stephen's Hospital, Glanmire, Co. Cork, Ireland
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Abstract

The clinical and pathological features are described in a case of prolonged dementia in a 59 year old man with familial dementia and extrapyramidal disorder. Postmortem examination showed severe fronto-temporal and basal ganglia atrophy, with many “ballooned neurons” in the residual cortex most likely representing Pick's disease. The differential diagnosis is discussed and aspects of this rare condition are reviewed.

Keywords

Atypical Pick's diseaseFamilial dementiaPick's cells.
Type
Clinical and Brief Reports
Information
Irish Journal of Psychological Medicine , Volume 11 , Issue 1 , March 1994 , pp. 34 - 38
Copyright
Copyright © Cambridge University Press 1994

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