English ivy (Hedera helix) is an evergreen, perennial vine that was introduced from Europe and Asia and is not endemic in much of the United States. English ivy can be invasive and difficult to control once established. Four similar, but not identical, experiments were conducted in sequence to evaluate selected, POST-applied herbicides for English ivy control. English ivy plants were propagated from cuttings and container-grown to obtain a large population of uniform plants. Aminopyralid and fluroxypyr applied at 1.34 and 0.71 kg ae ha−1, which is more twice the maximum registered rate for either herbicide, were ineffective. Glyphosate and 2,4-D amine were generally more effective, but neither herbicide provided a level of control that could be deemed consistently acceptable. Glyphosate applied at 8.51 kg ae ha−1 (the highest rate evaluated) provided 69, 98, and 89% control in the second, third, and fourth experiments as determined by foliage fresh-weight reduction relative to a nontreated control. Treatment with 2,4-D at 5.60 kg ae ha−1 (the highest rate evaluated) controlled English ivy 28, 98, and 89% in the second, third, and fourth experiments, respectively. Mixtures of 2,4-D and glyphosate were generally no more effective than were the components applied alone. Metsulfuron was the most effective herbicide. Metsulfuron applied at 0.168 kg ai ha−1 controlled English ivy ≥ 97% across the three experiments in which this treatment was included. This treatment also prevented regrowth.