This article investigates the relationship between social mobility and status in guilds and the political situation in sixteenth-century Ghent. First, it argues that Ghent guilds showed neither a static picture of upward mobility nor a rectilinear and one-way evolution. It demonstrates that the opportunities for social promotion within the guild system were, to a great extent, determined by the successive political regimes of the city. Second, the article proves that the guild boards in the sixteenth century had neither a typically oligarchic nor a typically democratic character. Third, the investigation of the houses in which master craftsmen lived shows that guild masters should not be depicted as a monolithic social bloc, but that significant differences in status and wealth existed. The article concludes that there was no linear positive connection between the duration of a master craftsman's career and his wealth and social position.