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The utility of the new research diagnostic criteria for Alzheimer's disease

Published online by Cambridge University Press:  13 November 2012

Bruno Dubois
Affiliation:
Institut de la Mémoire et de la Maladie d'Alzheimer, CRICM UMR-S975-APHP Salpêtrière Hospital, Paris, France
Serge Gauthier
Affiliation:
McGill Center for Studies in Aging, Douglas Mental Health Research Institute, Montreal, Canada
Jeffrey Cummings
Affiliation:
Cleveland Clinic Lou Ruvo Center for Brain Health at Las Vegas (Nevada), Cleveland (Ohio), and Weston (Florida), USA

Extract

Alzheimer's disease (AD) has traditionally been defined as a type of dementia, a concept reinforced by the publication of the National Institute of Neurological and Communicative Disorders and Stroke–Alzheimer's Disease and Related Disorders (NINCDS–ADRDA) criteria in 1984 (Isaac et al., 2011). Three major tenets of these criteria were that (i) the clinical diagnosis of AD cannot be made with certainty and requires post-mortem confirmation; (ii) for that reason, the clinical diagnosis of AD can only be “probable”; and (iii) the diagnosis can be made only when the disease is advanced and reaches the threshold of dementia.

Type
FOR DEBATE: IS VERY EARLY DIAGNOSIS OF AD USING THE NEW CRITERIA BENEFICIAL FOR PATIENTS?
Copyright
Copyright © International Psychogeriatric Association 2012

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