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Susceptibility Genetics in the Etiopathogenesis of Alzheimer's Disease: Role for Potential Confounding Factors

Published online by Cambridge University Press:  10 January 2005

Charles R. Harrington  and
Martin Roth
Charles R. Harrington
Affiliation:
Cambridge Brain Bank Laboratory, MRC Centre and Trinity College, Cambridge, England
Martin Roth
Affiliation:
Cambridge Brain Bank Laboratory, MRC Centre and Trinity College, Cambridge, England

Extract

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Finding genetic linkage and identifying the genes responsible for disease can revolutionize our understanding of disorders with obscure or complex etiology and pathogenesis (Weatherall, 1991). When relevant genes have been cloned, the identification of specific mutations that cause disease (Goate et al., 1991) enables molecular pathogenesis of the condition to be addressed.

Type
Guest Editorials
Information
International Psychogeriatrics , Volume 9 , Issue 3 , September 1997 , pp. 229 - 244
Copyright
© 1997 International Psychogeriatric Association