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The structure and validity of self-reported affect in mild cognitive impairment and mild Alzheimer's disease

Published online by Cambridge University Press:  24 March 2011

Rebecca E. Ready ,
Janessa O. Carvalho ,
Robert C. Green ,
Brandon E. Gavett  and
Robert A. Stern
Rebecca E. Ready*
Affiliation:
Department of Psychology, The University of Massachusetts, Amherst, Massachusetts, USA
Janessa O. Carvalho
Affiliation:
Department of Psychiatry and Human Behavior, Brown University Alpert School of Medicine, Providence, Rhode Island, USA
Robert C. Green
Affiliation:
Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA Department of Medicine (Geriatrics Program), Boston University School of Medicine, Boston, Massachusetts, USA Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA
Brandon E. Gavett
Affiliation:
Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA
Robert A. Stern
Affiliation:
Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA
*
Correspondence should be addressed to: Rebecca E. Ready, PhD, The University of Massachusetts, Department of Psychology, Tobin Hall, 135 Hicks Way, Amherst, MA 01003; Phone: +1 413-545-1359; Fax: +1 413-545-0996. Email: [email protected].
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Abstract

Background: This study determined the reliability, validity, and factor structure of self-report emotions in persons with mild Alzheimer's disease (AD) and mild cognitive impairment (MCI) relative to controls.

Methods: Participants (mild AD, n = 73; MCI, n = 159; controls, n = 96) rated current emotions with the Visual Analogue Mood Scales (Stern, 1997).

Results: Internal consistency reliabilities were comparable across groups, as were the factor structures of emotion. Persons with AD reported more negative affect (NA) than persons with MCI and controls. The emotion that most differentiated groups was confusion. NA and PA may be more bipolar in persons with AD than for persons with MCI and controls.

Conclusions: The underlying structure of affect was similar in persons with mild AD, MCI, and controls. Further, persons with MCI appeared to be “transitional” between cognitive health and dementia with regard to mood and affect. That is, participants with MCI tended to have affect scores that were intermediate between those with AD and controls. Implications for interventions to improve emotional well-being in AD and MCI are discussed.

Keywords

visual analogue scalespositive affectnegative affectfactor structureemotionself-reportdementia
Type
Research Article
Information
International Psychogeriatrics , Volume 23 , Issue 6 , August 2011 , pp. 887 - 898
Copyright
Copyright © International Psychogeriatric Association 2011

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References

Aikman, G. G. and Oehlert, M. E. (2001). Geriatric Depression Scale: long form versus short form. Journal of Aging and Mental Health, 22, 63–70.Google Scholar
Ashendorf, L., Jefferson, A. L., O'Connor, M. K., Chaisson, C., Green, R. C. and Stern, R. A. (2008). Trail Making Test errors in normal aging, mild cognitive impairment, and dementia. Archives of Clinical Neuropsychology, 23, 129–137.Google ScholarPubMed
Barnes, J., Whitwell, J. L., Frost, C., Josephs, K. A., Rossor, M. and Fox, N. C. (2006). Measurements of the amygdala and hippocampus in pathologically confirmed Alzheimer disease and frontotemporal lobar degeneration. Archives of Neurology, 63, 1434–1439.CrossRefGoogle ScholarPubMed
Beck, C. K. et al. (2002). Effects of behavioral interventions on disruptive behavior and affect in demented nursing home residents. Nursing Research, 51, 219–228.CrossRefGoogle ScholarPubMed
Brod, M., Stewart, A. L., Sands, L. and Walton, P. (1999). Conceptualization and measurement of quality of life in dementia: the Dementia Quality of Life instrument (DQoL). The Gerontologist, 39, 25–35.CrossRefGoogle ScholarPubMed
Cohen, J. (1992). A power primer. Psychological Bulletin, 112, 155–159.CrossRefGoogle ScholarPubMed
Crawford, J. R. and Henry, J. D. (2004). The Positive and Negative Affect Schedule (PANAS): construct validity, measurement properties and normative data in a large non-clinical sample. British Journal of Clinical Psychology, 43, 245–265.CrossRefGoogle Scholar
Everett, J. E. (1983). Factor comparability as a means of determining the number of factors and their rotation. Multivariate Behavioral Research, 18, 197–218.CrossRefGoogle ScholarPubMed
Federal Drug Administration (2006). Guidance for Industry Patient-Reported Outcome Measures: Use in Medical Product Development to Support Labeling Claims. Available at: http://www.fda.gov/cder/guidance/5460dft.htm.Google Scholar
Feinstein, J. S., Duff, M. C. and Tranel, D. (2010). Sustained experience of emotion after loss of memory in patients with amnesia. Proceedings of the National Academy of Sciences, 107, 7674–7679.CrossRefGoogle ScholarPubMed
Folstein, M. F., Folstein, S. E. and McHugh, P. R. (1975). “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatry Research, 12, 189–198.CrossRefGoogle ScholarPubMed
Heun, R., Kockler, M. and Ptok, U. (2002). Depression in Alzheimer's disease: is there a temporal relationship between onset of depression and onset of dementia? European Psychiatry, 17, 254–258.CrossRefGoogle Scholar
Hughes, C. P., Berg, L., Danziger, W. L., Coben, L. A. and Martin, R. L. (1982). A new clinical scale for the staging of dementia. British Journal of Psychiatry, 140, 566–572.CrossRefGoogle ScholarPubMed
Kolanowski, A., Hoffman, L. and Hofer, S. M. (2007). Concordance of self-report and informant assessment of emotional well-being in nursing home residents with dementia. Journal of Gerontology, 62B, P20–P27.CrossRefGoogle Scholar
Kørner, A. et al. (2006). The Geriatric Depression Scale and the Cornell Scale for Depression in Dementia: a validity study. Nordic Journal of Psychiatry, 60, 360–364.CrossRefGoogle ScholarPubMed
Kunzmann, U., Little, T. D. and Smith, J. (2000). Is age-related stability of subjective well-being a paradox? Cross-sectional and longitudinal evidence from the Berlin Aging Study. Psychology and Aging, 15, 511–526.CrossRefGoogle ScholarPubMed
Lawton, M. P. and Brody, E. M. (1969). Assessment of older people: self-maintaining and instrumental activities of daily living. The Gerontologist, 9, 179–186.CrossRefGoogle ScholarPubMed
Lawton, M. P., Van Haitsma, K. and Klapper, J. (1996). Observed affect in nursing home residents with Alzheimer's disease. Journals of Gerontology, 51B, P3–P14.CrossRefGoogle Scholar
Logsdon, R. G., Gibbons, L. E., McCurry, S. M. and Teri, L. (2002). Assessing quality of life in older adults with cognitive impairment. Psychosomatic Medicine, 64, 510–519.CrossRefGoogle ScholarPubMed
McKhann, G., Drachman, D., Folstein, M. F., Katzman, R., Price, D. and Stadlan, E. M. (1984). Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's disease. Neurology, 34, 939–944.CrossRefGoogle ScholarPubMed
Meyer, G. J. and Shack, J. R. (1989). Structural convergence of mood and personality: evidence for old and new directions. Journal of Personality and Social Psychology, 57, 691–706.CrossRefGoogle Scholar
Morris, J. C. (1993). The clinical dementia rating (CDR): current version and scoring rules. Neurology, 43, 2412–2414.CrossRefGoogle ScholarPubMed
Nyehius, D. L., Stern, R. A., Yamamoto, C., Luchetta, T. and Arruda, J. E. (1997). Standardization and validation of the Visual Analog Mood Scales. The Clinical Neuropsychologist, 11, 407–415.Google Scholar
Palmer, K. et al. (2010). Neuropsychiatric predictors of progression from amnestic-mild cognitive impairment to Alzheimer's disease: the role of depression and apathy. Journal of Alzheimer's Disease, 20, 175–183.CrossRefGoogle ScholarPubMed
Petersen, R. C. et al. (2009). Mild cognitive impairment: ten years later. Archives of Neurology, 66, 1447–1455.CrossRefGoogle ScholarPubMed
Ready, R. E., Ott, B. R. and Grace, J. (2004). Patient versus informant perspectives of quality of life in Mild Cognitive Impairment and Alzheimer's disease. International Journal of Geriatric Psychiatry, 19, 256–265.CrossRefGoogle ScholarPubMed
Ready, R. E., Ott, B. R. and Grace, J. (2007). Factor structure of patient and caregiver ratings on the Dementia Quality of Life Instrument. Aging, Neuropsychology, and Cognition, 14, 144–154.CrossRefGoogle ScholarPubMed
Rockwood, K., Strang, D., MacKnight, C., Downer, R. and Morris, J. C. (2000). Interrater reliability of the Clinical Dementia Rating in a multicenter trial. Journal of the American Geriatrics Society, 48, 558–559.CrossRefGoogle Scholar
Sands, L. P., Ferreira, P., Stewart, A. L., Brod, M. and Yaffe, K. (2004). What explains differences between dementia patients' and their caregivers' ratings of patient's quality of life? American Journal of Geriatric Psychiatry, 12, 272–280.CrossRefGoogle Scholar
Sheikh, J. I. and Yesavage, J. A. (1986). Geriatric Depression Scale (GDS): recent evidence and development of a shorter version. Clinical Gerontologist, 37, 819–820.Google Scholar
Stern, R. A. (1997). Visual Analog Mood Scales (VAMS) Professional Manual. Odessa, FL: Psychological Assessment Resources, Inc.Google Scholar
Sun, X. et al. (2008). Amyloid-associated depression: a prodromal depression of Alzheimer's disease? Archives of General Psychiatry, 65, 542–550.CrossRefGoogle Scholar
Tappen, R. M. and Barry, C. (1995). Assessment of affect in advanced Alzheimer's disease: the Dementia Mood Picture Test. Journal of Gerontological Nursing, 21, 44–46.CrossRefGoogle ScholarPubMed
Temple, R. O., Stern, R. A., Latham, J., Ruffolo, J. S., Arruda, J. E. and Tremont, G. (2004). Assessment of mood state in dementia by use of the Visual Analog Mood Scales (VAMS). American Journal of Psychiatry, 12, 527–530.Google Scholar
Watson, D. and Clark, L. A. (1992). On traits and temperament: general and specific factors of emotional experience and their relations to the five factor model. Journal of Personality, 60, 443–476.CrossRefGoogle ScholarPubMed
Watson, D. and Tellegen, A. (1985). Toward a consensual structure of mood. Psychological Bulletin, 98, 219–235.CrossRefGoogle Scholar
Watson, D., Clark, L. A. and Chmielewski, M. (2008). Structures of personality and their relevance to psychopathology. II. Further articulation of a comprehensive unified trait structure. Journal of Personality, 76, 1545–1586.CrossRefGoogle ScholarPubMed
Winblad, B., Palmer, K., Kivipelto, M., Jelic, V. and Fratiglioni, L. (2004). Mild cognitive impairment: beyond controversies, towards a consensus. Report of the International Working Group on Mild Cognitive Impairment. Journal of Internal Medicine, 256, 240–246.CrossRefGoogle Scholar