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Sleep and mood in older adults: coinciding changes in insomnia and depression symptoms

Published online by Cambridge University Press:  02 August 2017

Michael J. Li Open the ORCID record for Michael J. Li [Opens in a new window] ,
Afton Kechter ,
Richard E. Olmstead ,
Michael R. Irwin  and
David S. Black
Michael J. Li*
Affiliation:
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Afton Kechter
Affiliation:
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Richard E. Olmstead
Affiliation:
Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience, University of California, Los Angeles, California, USA Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
Michael R. Irwin
Affiliation:
Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience, University of California, Los Angeles, California, USA Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
David S. Black
Affiliation:
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
*
Correspondence should be addressed to: Michael J. Li, MPH, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N Soto Street, 3rd Floor, Los Angeles, CA 90032, USA. Phone: 323 442 8223. Email: [email protected].
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Abstract

The aim of this analysis was to test if changes in insomnia symptoms and global sleep quality are associated with coinciding changes in depressed mood among older adults. We report on results yielded from secondary analysis of longitudinal data from a clinical trial of older adults (N = 49) aged 55 to 80 years who reported at least moderate levels of sleep problems. All measures were collected at baseline and after the trial ten weeks later. We computed change scores for two separate measures of disturbed sleep, the Athens Insomnia Scale (AIS) and the Pittsburgh Sleep Quality Index (PSQI), and tested their association with change in depressed mood (Beck Depression Inventory-II; BDI-II) in two separate linear regression models adjusted for biological covariates related to sleep (sex, age, body mass index, and NF-κB as a biological marker previously correlated with insomnia and depression). Change in AIS scores was associated with change in BDI-II scores (β = 0.38, p < 0.01). Change in PSQI scores was not significantly associated with change in BDI-II scores (β = 0.17, p = 0.26). Our findings suggest that improvements over ten weeks in insomnia symptoms rather than global sleep quality coincide with improvement in depressed mood among older adults.

Keywords

insomniasleepdepressionmoodnuclear factor-kappa Bolder adults
Type
Brief Report
Information
International Psychogeriatrics , Volume 30 , Issue 3: Issue Theme: Psychosocial Interventions for Dementia , March 2018 , pp. 431 - 435
Copyright
Copyright © International Psychogeriatric Association 2017 

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