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Examination of the association between mental health, morbidity, and mortality in late life: findings from longitudinal community surveys

Published online by Cambridge University Press:  23 September 2014

Richard A. Burns*
Affiliation:
Centre for Research on Ageing, Health and Wellbeing, The Australian National University Canberra, ACT, Australia
Peter Butterworth
Affiliation:
Centre for Research on Ageing, Health and Wellbeing, The Australian National University Canberra, ACT, Australia
Colette Browning
Affiliation:
School of Primary Health Care, Faculty of Medicine, Nursing & Health Sciences, Monash University, Melbourne, VIC, Australia
Julie Byles
Affiliation:
Research Centre for Gender, Health and Ageing, University of Newcastle, Newcastle, NSW, Australia
Mary Luszcz
Affiliation:
Flinders Centre for Ageing Studies and Department of Psychology, Flinders University, Adelaide, SA, Australia
Paul Mitchell
Affiliation:
Centre for Vision Research, Westmead Millennium Institute and Department of Ophthalmology, The University of Sydney, Sydney, NSW, Australia
Jonathan Shaw
Affiliation:
Baker IDI Heart and Diabetes Institute, Melbourne, VIC, Australia
Kaarin J. Anstey
Affiliation:
Centre for Research on Ageing, Health and Wellbeing, The Australian National University Canberra, ACT, Australia
*
Correspondence should be addressed to: Dr Richard A. Burns, Centre for Research on Ageing, Health and Wellbeing, The Australian National University, Building 62A, Eggleston Road, Canberra 0200, ACT, Australia. Phone: +61-2-6125-3132; Fax: +61-2-6125-1558. Email: [email protected].

Abstract

Background:

Physical health has been demonstrated to mediate the mental health and mortality risk association. The current study examines an alternative hypothesis that mental health mediates the effect of physical health on mortality risk.

Methods:

Participants (N = 14,019; women = 91%), including eventual decedents (n = 3,752), were aged 70 years and older, and drawn from the Dynamic Analyses to Optimise Ageing (DYNOPTA) project. Participants were observed on two to four occasions, over a 10-year period. Mediation analysis compared the converse mediation of physical and mental health on mortality risk.

Results:

For men, neither physical nor mental health was associated with mortality risk. For women, poor mental health reported only a small effect on mortality risk (Hazard Risk (HR) = 1.01; p < 0.001); more substantive was the risk of low physical health (HR = 1.04; p < 0.001). No mediation effects were observed.

Conclusions:

Mental health effects on mortality were fully attenuated by physical health in men, and partially so in women. Neither mental nor physical health mediated the effect of each other on mortality risk for either gender. We conclude that physical health is a stronger predictor of mortality risk than mental health.

Type
Research Article
Copyright
Copyright © International Psychogeriatric Association 2014 

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References

Anstey, K. J. and Luszcz, M. A. (2002). Mortality risk varies according to gender and change in depressive status in very old adults. Psychosomatic Medicine, 64, 880888.Google ScholarPubMed
Anstey, K. J. et al. (2010). Cohort profile: the dynamic analyses to optimize ageing (DYNOPTA) project. International Journal of Epidemiology, 39, 4451.CrossRefGoogle ScholarPubMed
Barth, J., Schumacher, M. and Herrmann-Lingen, C. (2004). Depression as a risk factor for mortality in patients with coronary heart disease: a meta-analysis. Psychosomatic Medicine, 66, 802813.CrossRefGoogle ScholarPubMed
Bartoli, F. et al. (2013). Depression after stroke and risk of mortality: a systematic review and meta-analysis. Stroke Research and Treatment, 2013, doi: 10.1155/2013/862978.CrossRefGoogle Scholar
Batterham, P. J., Christensen, H. and Mackinnon, A. J. (2012). Mental health symptoms associated with morbidity, not mortality, in an elderly community sample. Social Psychiatry and Psychiatric Epidemiology, 47, 7985.CrossRefGoogle ScholarPubMed
Bebbington, P. E. (1998). Sex and depression. Psychological Medicine, 28, 18.CrossRefGoogle ScholarPubMed
Burns, R. A., Butterworth, P., Luszcz, M. and Anstey, K. J. (2013). Stability and change in level of probable depression and depressive symptoms in a sample of middle and older-aged adults. International Psychogeriatrics, 25, 303309.CrossRefGoogle Scholar
Burns, R. A., Mitchell, P., Shaw, J. and Anstey, K. (2014). Trajectories of terminal decline in the well-being of older women: the DYNOPTA project. Psychology and Aging, 29, 4456.CrossRefGoogle ScholarPubMed
Cuijpers, P. and Schoevers, R. A. (2004). Increased mortality in depressive disorders: a review. Current Psychiatry Reports, 6, 430437.CrossRefGoogle ScholarPubMed
Davidson, M. B. (2005). SF-36 and diabetes outcome measures. Diabetes Care, 28, 15361537.CrossRefGoogle ScholarPubMed
Garratt, A. M., Ruta, D. A., Abdalla, M. I., Buckingham, J. K. and Russell, I. T. (1993). The SF36 health survey questionnaire: an outcome measure suitable for routine use within the NHS? British Medical Journal, 306, 14401444.CrossRefGoogle ScholarPubMed
Gill, S. C. et al. (2006). Mental health and the timing of men's retirement. Social Psychiatry and Psychiatric Epidemiology, 41, 515522.CrossRefGoogle ScholarPubMed
Harris, E. C. and Barraclough, B. (1998). Excess mortality of mental disorder. The British Journal of Psychiatry, 173, 1153.CrossRefGoogle ScholarPubMed
Kappelle, L. J. et al. (1994). Prognosis of young adults with ischemic stroke. A long-term follow-up study assessing recurrent vascular events and functional outcome in the Iowa Registry of Stroke in Young Adults. Stroke, 25, 13601365.CrossRefGoogle ScholarPubMed
Kravitz, R. L. et al. (1992). Differences in the mix of patients among medical specialties and systems of care. Results from the medical outcomes study. Journal of the American Medical Association, 267, 16171623.CrossRefGoogle ScholarPubMed
Noale, M. et al. (2005). Predictors of mortality: an international comparison of socio-demographic and health characteristics from six longitudinal studies on aging: the CLESA project. Experimental Gerontology, 40, 8999.CrossRefGoogle ScholarPubMed
Osborn, D. P. et al. (2002). Geriatric Depression Scale scores in a representative sample of 14,545 people aged 75 and over in the United Kingdom: results from the MRC trial of assessment and management of older people in the community. International Journal of Geriatric Psychiatry, 17, 375382.CrossRefGoogle Scholar
Osthus, T. B. et al. (2012). Mortality and health-related quality of life in prevalent dialysis patients: comparison between 12-items and 36-items short-form health survey. Health and Quality of Life Outcomes, 10, 46.CrossRefGoogle ScholarPubMed
Pachana, N. A., McLaughlin, D., Leung, J., Byrne, G. and Dobson, A. (2012). Anxiety and depression in adults in their eighties: do gender differences remain? International Psychogeriatrics, 24, 145150.CrossRefGoogle ScholarPubMed
Pinquart, M. and Duberstein, P. R. (2010). Depression and cancer mortality: a meta-analysis. Psychological Medicine, 40, 17971810.CrossRefGoogle ScholarPubMed
Rumpf, H. J., Meyer, C., Hapke, U. and John, U. (2001). Screening for mental health: validity of the MHI-5 using DSM-IV Axis I Psychiatric Disorders as gold standard. Psychiatry Research, 105, 243253.CrossRefGoogle ScholarPubMed
Saz, P. and Dewey, M. E. (2001). Depression, depressive symptoms and mortality in persons aged 65 and over living in the community: a systematic review of the literature. International Journal of Geriatric Psychiatry, 16, 622630.CrossRefGoogle ScholarPubMed
Skapinakis, P., Lewis, G., Araya, R., Jones, K. and Williams, G. (2005). Mental health inequalities in Wales, UK: multi-level investigation of the effect of area deprivation. British Journal of Psychiatry, 186, 417422.CrossRefGoogle ScholarPubMed
van't Veer-Tazelaar, P. J. et al. (2008). Depression in old age (75+), the PIKO study. Journal of Affective Disorders, 106, 295299.CrossRefGoogle ScholarPubMed
Viramontes, J. L. and O’Brien, B. (1994). Relationship between symptoms and health-related quality of life in chronic lung disease. Journal of General Internal Medicine, 9, 4648.CrossRefGoogle ScholarPubMed
Ware, J. E. Jr., et al. (1998). The factor structure of the SF-36 Health Survey in 10 countries: results from the IQOLA Project. International Quality of Life Assessment. Journal of Clinical Epidemiology, 51, 11591165.CrossRefGoogle ScholarPubMed
Wulsin, L. R., Vaillant, G. E. and Wells, V. E. (1999). A systematic review of the mortality of depression. Psychosomatic Medicine, 61, 617.CrossRefGoogle ScholarPubMed
Zhang, J. P., Pozuelo, L., Brennan, D. M., Hoar, B. and Hoogwerf, B. J. (2010). Association of SF-36 with coronary artery disease risk factors and mortality: a PreCIS study. Preventive Cardiology, 13, 122129.Google ScholarPubMed
Zunzunegui, M. V. et al. (2007). Gender differences in depressive symptoms among older adults: a cross-national comparison: the CLESA project. Social Psychiatry and Psychiatric Epidemiology, 42, 198207.CrossRefGoogle ScholarPubMed