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Dementia clinical trial implications of mild behavioral impairment

Published online by Cambridge University Press:  16 February 2018

Moyra E. Mortby
Affiliation:
Centre for Research on Ageing, Health and Wellbeing, Research School of Population Health, The Australian National University, Canberra, Australia NHMRC National Institute for Dementia Research, Canberra, Australia
Sandra E. Black
Affiliation:
Department of Medicine (Neurology), Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, Sunnybrook HSC, University of Toronto, Toronto, Canada
Serge Gauthier
Affiliation:
McGill Center for Studies in Aging, Douglas Mental Health Research Institute, Montreal, Canada
David Miller
Affiliation:
Bracket Global, Wayne, Pennsylvania, USA
Anton Porsteinsson
Affiliation:
Alzheimer's Disease Care, Research and Education Program (AD-CARE), University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
Eric E. Smith
Affiliation:
Department of Clinical Neurosciences, Ron and Rene Ward Centre for Healthy Brain Aging, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada
Zahinoor Ismail*
Affiliation:
Department of Clinical Neurosciences, Ron and Rene Ward Centre for Healthy Brain Aging, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada Department of Psychiatry, Mathison Centre for Mental Health Research & Education, University of Calgary, Calgary, Canada
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The World Alzheimer Report 2016 estimated that 47 million people are living with dementia worldwide (Alzheimer's Disease International, 2016). In the inaugural World Health Organization Ministerial Conference on Global Action against Dementia, six of the top ten research priorities were focused on prevention, identification, and reduction of dementia risk, and on delivery and quality of care for people with dementia and their carers (Shah et al., 2016). While the Lancet Neurology Commission has suggested that even minor advances to delay progression or ameliorate symptoms might have substantial financial and societal benefits (Winblad et al., 2016), advances have been slow.

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Commentary
Copyright
Copyright © International Psychogeriatric Association 2018 

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