Hostname: page-component-78c5997874-ndw9j Total loading time: 0 Render date: 2024-11-20T02:40:23.131Z Has data issue: false hasContentIssue false

The conundrum of depressive symptom-frailty comorbidity and overlap

Published online by Cambridge University Press:  01 October 2021

Rhian Milton-Cole*
Affiliation:
Department of Population Health Sciences, School of Population Health and Environmental Sciences, King’s College London, London, UK
Brendon Stubbs
Affiliation:
Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK Physiotherapy Department, South London, and Maudsley NHS Foundation Trust, London, UK

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Commentary
Copyright
© International Psychogeriatric Association 2021

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Buigues, C., Padilla-Sanchez, C., Garrido, J. F., Navarro-Martinez, R., Ruiz-Ros, V. and Cauli, O. (2015). The relationship between depression and frailty syndrome: a systematic review. Aging & Mental Health, 19, 762772. DOI 10.1080/13607863.2014.967174.CrossRefGoogle ScholarPubMed
Chang, C. C. et al. (2021). Assessment of incident frailty hazard associated with depression in a Taiwanese longitudinal study. International Psychogeriatrics, 34, 6170. DOI 10.1017/S1041610221000806.Google Scholar
Chu, W., Chang, S.-F., Ho, H.-Y. and Lin, H.-C. (2019). The relationship between depression and frailty in community-dwelling older people: a systematic review and meta-analysis of 84,351 older adults. Journal of Nursing Scholarship, 51, 547559. DOI 10.1111/jnu.12501.CrossRefGoogle ScholarPubMed
Cosco, T. D. et al. (2020). Latent structure of the Centre for Epidemiologic Studies Depression Scale (CES-D) in older adult populations: a systematic review. Aging & Mental Health, 24, 700704. DOI 10.1080/13607863.2019.1566434.CrossRefGoogle ScholarPubMed
Feng, Z. et al. (2017). Risk factors and protective factors associated with incident or increase of frailty among community-dwelling older adults: a systematic review of longitudinal studies. PLoS One, 12, e0178383. DOI 10.1371/journal.pone.0178383.CrossRefGoogle ScholarPubMed
Firth, J. et al. (2020). A meta-review of “lifestyle psychiatry”: the role of exercise, smoking, diet and sleep in the prevention and treatment of mental disorders. World Psychiatry, 19, 360380. DOI 10.1002/wps.20773.CrossRefGoogle ScholarPubMed
Köhler, C. A. et al. (2017). Peripheral cytokine and chemokine alterations in depression: a meta-analysis of 82 studies. Acta Psychiatrica Scandinavica, 135, 373387. DOI 10.1111/acps.12698.CrossRefGoogle ScholarPubMed
Lohman, M., Dumenci, L. and Mezuk, B. (2016). Depression and frailty in late life: evidence for a common vulnerability. The Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 71, 630640. DOI 10.1093/geronb/gbu180.CrossRefGoogle ScholarPubMed
Mezuk, B., Edwards, L., Lohman, M., Choi, M. and Lapane, K. (2012). Depression and frailty in later life: a synthetic review. International Journal of Geriatric Psychiatry, 27, 879892. DOI 10.1002/gps.2807.CrossRefGoogle ScholarPubMed
Mezuk, B., Lohman, M., Dumenci, L. and Lapane, K. L. (2013). Are depression and frailty overlapping syndromes in mid- and late-life? A latent variable analysis. The American Journal of Geriatric Psychiatry, 21, 560569. DOI 10.1016/j.jagp.2012.12.019.CrossRefGoogle ScholarPubMed
Soysal, P. et al. (2016). Inflammation and frailty in the elderly: a systematic review and meta-analysis. Ageing Research Reviews, 31, 18. DOI 10.1016/j.arr.2016.08.006.CrossRefGoogle ScholarPubMed
Soysal, P. et al. (2017). Relationship between depression and frailty in older adults: a systematic review and meta-analysis. Ageing Research Reviews, 36, 7887. DOI 10.1016/j.arr.2017.03.005.CrossRefGoogle ScholarPubMed
Stubbs, B., Brefka, S., Dallmeier, D., Stubbs, J., Vancampfort, D. and Denkinger, M. D. (2016). Depression and reduced bone mineral density at the hip and lumbar spine: a comparative meta-analysis of studies in adults 60 years and older. Psychosomatic Medicine, 78, 492500. DOI 10.1097/PSY.0000000000000292.CrossRefGoogle ScholarPubMed
Stubbs, B. et al. (2020). Risk of hospitalized falls and hip fractures in 22,103 older adults receiving mental health care vs 161,603 controls: a large cohort study. Journal of the American Medical Directors Association, 21, 18931899. DOI 10.1016/j.jamda.2020.03.005.CrossRefGoogle ScholarPubMed
Zhang, N. et al. (2020). Depressive symptoms are associated with incident frailty in a Chinese population: the Rugao longevity and aging study. Aging Clinical and Experimental Research, 32, 22972302. DOI 10.1007/s40520-019-01409-x.CrossRefGoogle Scholar