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Bupropion in the treatment of depression in Parkinson's disease

Published online by Cambridge University Press:  01 September 2010

Maria Załuska  and
Agnieszka Dyduch
Maria Załuska
Affiliation:
IV Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland
Agnieszka Dyduch*
Affiliation:
Department of Psychiatry, Bielański Hospital, Warsaw, Poland
*
Correspondence should be addressed to: Agnieszka Dyduch, Oddział Psychiatrii, Szpital Bielański, Cegłowska 80, 01-809 Warsaw, Poland. Phone: +48 601 178 946; Fax. +48 22 864 47 46. Email: [email protected].
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Abstract

A 78-year-old female with a nine-year history of depression was hospitalized due to worsening depression and symptoms associated with Parkinson's disease (PD). Her motor abilities improved on levodopa and the depression improved after a trial of bupropion, following unsuccessful treatment with other antidepressants. We found four reports on successful treatment of depression in PD with bupropion. However, no controlled double-blind studies have been conducted so clinicians should be cautious when administering bupropion in depression in PD.

Keywords

extrapyramidal syndromedepressive symptomspharmacotherapy
Type
Case Report
Information
International Psychogeriatrics , Volume 23 , Issue 2 , March 2011 , pp. 325 - 327
Copyright
Copyright © International Psychogeriatric Association 2010

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