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The association between congestive heart failure and cognitive performance in a primary care population of elderly adults: the Steel Valley Seniors Survey

Published online by Cambridge University Press:  10 May 2006

Laurie Lavery
Affiliation:
Division of Geriatric Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, U.S.A.
Joni Vander Bilt
Affiliation:
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, U.S.A.
Chung-Chou H. Chang
Affiliation:
Departments of Medicine and Biostatistics, University of Pittsburgh School of Medicine, Pittsburgh, PA, U.S.A.
Judith A. Saxton
Affiliation:
Departments of Neurology and Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, U.S.A.
Mary Ganguli
Affiliation:
Departments of Psychiatry and Epidemiology, University of Pittsburgh School of Medicine and Graduate School of Public Health, WPIC, Pittsburgh, PA, U.S.A.

Abstract

Background: Evidence suggests an association between congestive heart failure (CHF) and cognitive function, particularly in heart transplant patients and patients hospitalized for CHF. We examined the association between CHF and cognitive performance in stable outpatients recruited from primary care.

Methods: This is a cross-sectional secondary data analysis of the Steel Valley Seniors Survey, an epidemiological study of elderly primary care outpatients. Participants aged ≥ 65 years were recruited in primary care clinics. The study cohort (n = 354) is a subgroup, composed of subjects with Mini-mental State Examination score < 25, and a random sample of the remaining, who underwent a baseline assessment in the home. The assessment included demographics, comorbid illnesses, depressive symptoms, functional status, a neurological examination and a neuropsychological battery. CHF is defined by self-report and/or chart review, and stable CHF as not being hospitalized in the year prior to the assessment. The associations between CHF and specific cognitive tests were examined by bivariate analysis and logistic regression, controlling for demographic variables.

Results: Subjects with CHF performed worse on tests of visual memory [10.1 (S.D. 5.4) vs. 12.7 (S.D. 5.2), p = 0.007], Trailmaking B [0.1 (0.1) vs. 0.2 (0.1), p = 0.002], category fluency [11.1 (4.4) vs. 13.4 (4.5), p = 0.008], and clock drawing [5.6 (1.9) vs. 6.7 (1.4), p < 0.001] compared to subjects without CHF, after adjustment for relevant demographic variables.

Conclusion: CHF is associated with lower cognitive functioning in a population of patients with stable heart failure in primary care settings.

Type
Research Article
Copyright
International Psychogeriatric Association 2007

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