Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-22T19:47:27.806Z Has data issue: false hasContentIssue false
  • English
  • Français

Adjunct treatment with levodopa in a patient with dementia with Lewy bodies, delusions and severe neuroleptic hypersensitivity syndrome

Published online by Cambridge University Press:  04 March 2010

Tomislav Majic ,
Thomas Mell ,
Andreas Heinz  and
Michael A. Rapp
Tomislav Majic
Affiliation:
Department of Psychiatry, Charité – University Medicine Berlin, Campus Charité Mitte, Berlin, Germany
Thomas Mell
Affiliation:
Department of Psychiatry, Charité – University Medicine Berlin, Campus Charité Mitte, Berlin, Germany
Andreas Heinz
Affiliation:
Department of Psychiatry, Charité – University Medicine Berlin, Campus Charité Mitte, Berlin, Germany
Michael A. Rapp*
Affiliation:
Department of Psychiatry, Charité – University Medicine Berlin, Campus Charité Mitte, Berlin, Germany
*
Correspondence should be addressed to: Michael A. Rapp, MD, PhD, Department of Psychiatry and Psychotherapy, Charité University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany. Phone: +49 30 2311 2959; Fax: +49 30 2311 2952. Email: [email protected].
Get access

Abstract

We report on the treatment of a patient suffering from dementia with Lewy bodies who initially presented with severe neurological and psychopathological symptoms. After treating the patient with levodopa and clozapine, these symptoms remitted.

Keywords

Lewy body dementianeuroleptic hypersensitivitylevodopa
Type
Case Report
Information
International Psychogeriatrics , Volume 22 , Issue 4 , June 2010 , pp. 678 - 679
Copyright
Copyright © International Psychogeriatric Association 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ballard, C., Grace, J., McKeith, I. and Holmes, C. (1998). Neuroleptic sensitivity in dementia with Lewy bodies and Alzheimer's disease. Lancet, 351, 1032–1033.CrossRefGoogle ScholarPubMed
Burke, W. J., Pfeiffer, R. F. and McComb, R. D. (1998). Neuroleptic sensitivity to clozapine in dementia with Lewy bodies. Journal of Neuropsychiatry and Clinical Neuroscience, 10, 227–229.CrossRefGoogle ScholarPubMed
Borroni, B. et al. (2006). Primitive reflex evaluation in the clinical assessment of extrapyramidal syndromes. European Journal of Neurology, 13, 1026–1028.CrossRefGoogle ScholarPubMed
Magnusson, T. M., Keller, B. K. and Burke, W. J. (1998). Extrapyramidal side effects in a patient treated with risperidone plus donepezil. American Journal of Psychiatry, 155, 1458–1459.CrossRefGoogle Scholar
McKeith, I., Fairbairn, A., Perry, R., Thompson, P., and Perry, E. (1992). Neuroleptic sensitivity in patients with senile dementia of Lewy body type. BMJ, 305, 673–678.CrossRefGoogle ScholarPubMed
McKeith, I. et al. (2000). Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo-controlled international study. Lancet, 356, 2031–2036.CrossRefGoogle ScholarPubMed
McKeith, I. et al. (2005). Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology, 65, 1863–1872.CrossRefGoogle ScholarPubMed
Molloy, S., McKeith, I. G., O'Brien, J. T. and Burn, D. J. (2005). The role of levodopa in the management of dementia with Lewy bodies. Journal of Neurology, Neurosurgery and Psychiatry, 76, 1200–1203.CrossRefGoogle ScholarPubMed
Sadek, J. and Rockwood, K. (2003). Coma with accidental single dose of an atypical neuroleptic in a patient with Lewy body dementia. American Journal of Geriatric Psychiatry, 11, 112–113.CrossRefGoogle Scholar