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Sleep quality in caregivers of patients with Alzheimer's disease and Parkinson's disease and its relationship to quality of life

Published online by Cambridge University Press:  01 June 2012

Chiara Cupidi ,
Sabrina Realmuto ,
Gianluca Lo Coco ,
Antonio Cinturino ,
Simona Talamanca ,
Valentina Arnao ,
Valentina Perini ,
Marco D'Amelio ,
Giovanni Savettieri  and
Daniele Lo Coco
Chiara Cupidi
Affiliation:
Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche (BioNeC), Università di Palermo, Palermo, Italy
Sabrina Realmuto
Affiliation:
Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche (BioNeC), Università di Palermo, Palermo, Italy
Gianluca Lo Coco
Affiliation:
Department of Psychology, Università di Palermo, Palermo, Italy
Antonio Cinturino
Affiliation:
Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche (BioNeC), Università di Palermo, Palermo, Italy
Simona Talamanca
Affiliation:
Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche (BioNeC), Università di Palermo, Palermo, Italy
Valentina Arnao
Affiliation:
Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche (BioNeC), Università di Palermo, Palermo, Italy
Valentina Perini
Affiliation:
Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche (BioNeC), Università di Palermo, Palermo, Italy
Marco D'Amelio
Affiliation:
Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche (BioNeC), Università di Palermo, Palermo, Italy
Giovanni Savettieri
Affiliation:
Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche (BioNeC), Università di Palermo, Palermo, Italy
Daniele Lo Coco*
Affiliation:
Sleep Disorders Clinic, Dipartimento di Neuroscienze, Ospedale Civico – ARNAS, Palermo, Italy
*
Correspondence should be addressed to: Dr. Daniele Lo Coco, MD, PhD, Sleep Disorders Clinic, Dipartimento di Neuroscienze, Ospedale Civico – ARNAS, P.za N. Leotta, 4 – 90129 Palermo, Italy. Phone: +39 091 666 3005; Fax: +39 091 666 3006. Email: [email protected].
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Abstract

Background: Knowledge about sleep complaints of caregivers of patients with Alzheimer's disease (AD) and Parkinson's disease (PD) is limited, and we lack information about the relationship between caregivers’ sleep problems and their quality of life (QoL).

Methods: We evaluated subjective sleep quality and its relationship to QoL in a group of 80 caregivers of patients with AD (ADCG, n = 40) and PD (PDCG, n = 40), and in 150 controls. Information about night-time complaints was collected using the Pittsburgh Sleep Quality Index (PSQI). QoL was measured using the McGill QoL Questionnaire.

Results: Eighteen ADCG (45%), 22 PDCG (55%), and 45 (30%) controls reported poor sleep quality. Mean global PSQI score of PDCG (6.25 ± 3.9) was not significantly different from that of ADCG (5.8 ± 3.5; p = 0.67). However, both PDCG and ADCG scored significantly higher than control group (4.3 ± 3.1; p < 0.01). ADCG frequently reported difficulties falling asleep (72.5%) and disturbed sleep (100%). PDCG reported reduced subjective sleep quality (80%) and increased sleep disturbances (100%). Poor sleep quality was associated with depressive symptoms and correlated with QoL in caregivers of both groups, particularly the psychological symptoms domain.

Conclusions: Among caregivers of patients with AD and PD, poor sleep quality is frequent and significantly linked to QoL and depressive symptoms. Identifying the nature of sleep disturbances not only in patients but also in their caregivers is important as appropriate treatment may lead to a better management of the needs of families coping with these patients.

Keywords

Alzheimer's diseaseParkinson's diseaseneurodegenerative disorderscaregiverssleepdepressionquality of life
Type
Research Article
Information
International Psychogeriatrics , Volume 24 , Issue 11 , November 2012 , pp. 1827 - 1835
Copyright
Copyright © International Psychogeriatric Association 2012

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