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Assessment of Executive Function in Clinical Trials

Published online by Cambridge University Press:  10 January 2005

Raija Ylikoski
Affiliation:
Helsinki University Central Hospital, Department of Neurology, HUS, Finland
Tuomo Hänninen
Affiliation:
Department of Neurology, Kuopio University Hospital, Kuopio, Finland

Abstract

Cerebrovascular disease and stroke are related to high risk of cognitive impairment. One of the main neuropsychological features in vascular cognitive impairment and vascular dementia is executive dysfunction. Definition of the essential subcomponents and concepts of executive function is important before determining the methodology in clinical trials. The scientific research and new methods on this topic are rapidly growing. We present some most commonly used neuropsychological tests and discuss the methodological aspects in light of clinical trials.

Type
TRIAL DESIGNS: SYMPTOMATIC
Copyright
© 2003 International Psychogeriatric Association

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