INVENTHEI (INnoVation and ENTrepreneurship in Higher Education Institutions) is an European project aimed to enhance the regional innovation ecosystems and promote innovation-driven research. In Spain, the University of Santiago de Compostela participates through the Master’s Degree in Psychogerontology (Faculty of Psychology) and the Master’s Degree in Gerontology (Faculty of Nursing). Learning and mentoring programme related with the ageing process is presented, focused on the social innovation and transfer capacities of our students, faculty and staff members. A challenged based multidisciplinary learning method is followed, including three training sessions (Session 1: Person- centred innovation; Session 2: Team-centred innovation; Session 3: Results-centred innovation) and online mentoring. Using this methodology, transfer of the learning is promoted in an agile and practical way through the resolution of challenges proposed by external partners in the sector of gerontology and healthcare. The social innovation-training programme is complemented with a workshop about innovation driven research in aging and presentation of business cases, involving the organizational ecosystem of the sector.