Hostname: page-component-cd9895bd7-8ctnn Total loading time: 0 Render date: 2024-12-23T16:16:08.741Z Has data issue: false hasContentIssue false

Toxicity and growth-inhibitory activity of Polygonum senegalense (Meissn.) surface exudate against Aedes aegypti larvae

Published online by Cambridge University Press:  19 September 2011

Nicholas K. Gikonyo
Affiliation:
Departments of Chemistry, and University of Nairobi P. O. Box 30197, Nairobi, Kenya
Richard W. Mwangi
Affiliation:
Departments of Zoology, University of Nairobi P.O. Box 30197, Nairobi, Kenya
J. Ogweno Midiwo*
Affiliation:
Departments of Chemistry, and University of Nairobi P. O. Box 30197, Nairobi, Kenya
Get access

Abstract

Laboratory studies were conducted to assess the toxicity and growth-inhibitory activity against Aedes aegypti larvae, of the crude acetone extracts of Polygonum senegalense (Meissn.) leaves, its flavonoid component 2',6'-dihydroxy-4'-methoxydihydrochalcone and the internal tissue flavanol quercetin. The first two showed significantly high insecticidal and growth-inhibitory activity even at low concentrations, whereas quercetin was toxic only at concentrations above 7μg/ml.

Résumé

Des études au laboratoire ont été menées pour déceler l'effet toxique et inhibiteur de croissance chez les larves d' Aedes aegypti, par emploi des extraits bruts à l'acétone obtenus des feuilles de Polygonum senegalense (Meissn.) et en comparaison avec ses composants flavonoïdes: 2',6'-dihydroxy-4'-méthoxydihydrochalcone et du flavonol quercitine des tissus internes de la plante. Les deux premiers produits ont montré une activité hautement significative du pouvoir insecticide et d'effet inhibiteur de croissance même à des basses concentrations, au moment où la quercitine était seulement toxique à des concentrations supérieures à 7 μg/ml.

Type
Research Articles
Copyright
Copyright © ICIPE 1998

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Dossaji, S. and Kubo, I. (1980) Quercetin-3-(2“-galloylglucoside), a molluscicidal flavonoid from Polygonum senegalense. Phytochemistry 19, 482.CrossRefGoogle Scholar
Fukuyuma, Y., Sato, T., Asekawa, Y. and Takemoto, T. (1983) Potent cytotoxic warbuganal and related drimane type sesquiterpenoids from P. hydropiper. Phytochemistry 21, 2895.CrossRefGoogle Scholar
Midiwo, J. O., Matasi, J. J., Wanjau, O. M., Mwangi, R. W., Waterman, P. G. and Wollenweber, E. (1990) Anti-feedant effect of Polygonum senegalense. Bull. Chem. Soc. Ethiop. 4, 123127.Google Scholar
Midiwo, J. O., Gikonyo, N. K., Wanjau, O. M., Matasi, J. J. and Waterman, P. G. (1992) Flavonoids of Polygonum senegalense (Meissn.) Part II: More surface and internal tissue flavonoid aglycones. Bull. Chem. Soc. Ethiop. 6, 119122.Google Scholar
Mwangi, R. W. and Mukiama, T. K. (1988) Evaluation of Melia volkensii extract fractions as mosquito larvicides. J. Am. Mosq. Control Assoc. 4, 442447.Google ScholarPubMed
Mwangi, R. W. and Rembold, H. (1988) Growth inhibiting and larvicidal effects of Melia volkensii extracts on Aedes aegypti larvae. Entomol Exp. Appl. 46, 103108.CrossRefGoogle Scholar
Turill, W. B. and Milne-Redhead, E. (Eds) (1958) Polygonaceae. In Flora of Tropical East Africa. Crown Agents for Overseas Governments and Administration, London.Google Scholar
Wollenweber, E. (1985) Flavonoid aglycones as leaf exudate constituents in higher plants, pp. 155169. In Flavonoids and Bioflavonoids (Edited by Farkas, L., Gabor, M. and Kallay, F.). Institute of Botany, University of Darmstadt D-610U, Darmstadt, FRG.Google Scholar
Wollenweber, E., Hradetsky, E., Mann, K., Roitman, J. N., Yatskievitch, G. and Proksch, P. (1987) Exudate flavonoids from aerial parts of five Ambrosia species, J. Plant Physiol. 131, 3743.CrossRefGoogle Scholar
Zebitz, C. P. W. (1986) Effect of three neem seed kernel extracts and azadirachtin on larvae of different mosquito species. J. Appl. Entomol. 102, 445463.CrossRefGoogle Scholar