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Receptors mediating host-seeking behaviour in mosquitoes and their regulation by endogenous hormones

Published online by Cambridge University Press:  19 September 2011

E. E. Davis ,
D. A. Haggart  and
M. F. Bowen
E. E. Davis
Affiliation:
SRI International, Menlo Park, CA 94025, USA
D. A. Haggart
Affiliation:
SRI International, Menlo Park, CA 94025, USA
M. F. Bowen
Affiliation:
SRI International, Menlo Park, CA 94025, USA
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Abstract

The behavioural process by which a mosquito finds a potential host organism is mediated by olfactory receptors on the insect's antennae. Lactic acid (LA) is a host-related odour common to all potential hosts. On the antennae of the female are two LA-sensitive neurons; one of these is excited by LA but the other is inhibited by LA. Furthermore, the sensitivity of the LA-excited neuron is correlated 1:1 with the presence of host-seeking behaviour such that when host-seeking behaviour is inhibited following a blood meal, the sensitivity of the LA-excited neuron is markedly decreased. The inhibition of host-seeking behaviour and the decrease in LA-sensitivity are induced by a hemolymph-borne factor released during oocyte maturation. The source of this factor is the fat body of blood-fed females, which requires a vitellogenic ovary for its production and/or release. The combined activity of the two types of LA-sensitive neurons together with the shift in sensitivity of the LA-excited neuron from a range where host levels of LA are present to a range exceeding LA levels expected from a host are sufficient to account for the inhibition of host-seeking behaviour following a blood meal.

Résumé

La conduite par laquelle le moustique se trouve an hote-organisme potentiel, est entremis par des recepteurs olfactif sur les antennes de l'insecte. Lactique-acide (LA) est un hote-rapport, une odeur commune de l'hote-rapport a tous les hotes potentiel. Sur l'antenne de la femelle, il y a deux neurons LA-sensitif; seulement un des deux est excite par le LA, mais l'autre est arrete par le LA. En outre, la sensitivitie due neuron LA-excite corresponds 1:1 avec la presence de l'hote-chercheur et sa conduite est tel, que lorsque la conduite de l'hote-chercheur est inhibite apres un repas sanguin, la sensitivite du neuron LA-excite est tres diminuee. L'inhibition de la conduite de l'hote-chercheur et le decroissement dans la sensitivitie sont introduit par un nouveau agent, hemolymph, qui est decharge pendant la maturite de l'oocyte. La source de cet agent est la graisse des femelles nourrie par le sang, qui demande une ovaire vitellogenique pour sa production et/ou replacement. Les activites combinees de ces deux types: neurons de LA-sensitif avec la difference dans la sensitivite des neurons LA-excite d'un rang depuis un niveau ou les niveaux de l'hote avec le LA sont present a un rang excedant le niveau LA expecte d'un hote sont suffisant pour expliquer l'inhibition de la conduite de l'hote-chercheur apres un repas sanguin.

Keywords

Mosquitoeshost-seeking behaviourolfactory receptorsregulation of behaviourhormonesMoustiquesconduite de l'hote-chercheurrecepteur olfactifregulation de conduitehormones
Type
Symposium V: Host-seeking Mechanisms of Arthropods of Medical and Veterinary Importance
Information
International Journal of Tropical Insect Science , Volume 8 , Issue 4-5-6: Recent Advances in Research on Tropical Entomology , December 1987 , pp. 637 - 641
Copyright
Copyright © ICIPE 1987

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References

REFERENCES

Boeckh, J., Kaissling, K.-E. and Schneider, D. (1965) Insect olfactory receptors. Cold Springs Harbour Symp. Quant. Biol. 30, 263–280.Google Scholar
Camhi, J. M. (1984) Neuroethology. Sinauer Assoc. Publishers, Sunderland, MA, pp. 259–264.Google Scholar
Davis, E. E. (1984a) Development of lactic acid-receptor sensitivity and host-seeking behavior in newly emerged female Aedes aegypti mosquitoes. J. Insect Physiol. 30, 211–215.CrossRefGoogle Scholar
Davis, E. E. (1984b) Regulation of sensitivity in the peripheral chemoreceptor systems for host-seeking behavior by a haemolymph-borne factor in Aedes aegypti. J. Insect Physiol. 30, 179–183.Google Scholar
Davis, E. E. (1984c) Peripheral chemoreceptors and regulation of insect behavior. In Mechanisms in Insect Olfactory Orientation. (Edited by Payne, T. L., Birch, M. C. and Kennedy, C. E. J.) pp. 243–251. Oxford Univ. Press, Oxford.Google Scholar
Davis, E. E. (1985) Insect repellents: concepts of their mode of action relative to potential sensory mechanisms in mosquitoes. J. Med. Ent. 22, 237–243.Google Scholar
Davis, E. E. and Bowen, M. F. (1986) Hormonal regulation of receptor sensitivity and host-seeking behavior in mosquitoes: Role of the fat body. In Host Regulated Developmental Mechanisms in Vector Arthropods. (Borovsky, D. and Spielman, A.) pp. 135–141. University of Florida, Vero Beach.Google Scholar
Davis, E. E. and Sokolove, P. G. (1975) Temperature response of the antennal receptors in the mosquito, Aedes aegypti. J. Comp. Physiol. 96, 223–236.CrossRefGoogle Scholar
Davis, E. E. and Sokolove, P. G. (1976) Lactic acid-sensitive receptors on the antennae of the mosquito, Aedes aegypti. J. Comp. Physiol. 105, 43–54.Google Scholar
Dittmer, D. D. (1961) Biological handbooks: blood and other body fluids. Fed. Amer. Soc. Exp. Biol, Washington, D.C., pp. 467–473.Google Scholar
Feinsod, F. M. and Spielman, A. (1979) An olfactometer for measuring host-seeking behavior of female Aedes aegypti. J. Med. Ent. 15, 282–285.Google Scholar
Geddes, L. A. and Baker, L. E. (1968) Principles of Applied Biomedicai Instrumentation. John Wiley and Sons, New York, pp. 365–377.Google Scholar
Kandel, E. R., Krasne, F. B., Strumwasser, F. and Truman, J. W. (1979) Cellular mechanisms in the selection and modulation of behavior. Neurosci. Res. Program Bull. 17, 523–710.Google ScholarPubMed
Klowden, M. J. and Lea, A. O. (1979a) Abdominal distention terminates subsequent host-seeking behavior of Aedes aegypti following a blood meal. J. Insect Physiol. 25, 583–585.Google Scholar
Klowden, M. J. and Lea, A. O. (1979b) Humoral inhibition of host-seeking in Aedes aegypti during oocyte maturation. J. Insect Physiol. 25, 231–235.Google Scholar
Klowden, M. J., Davis, E. E. and Bowen, M. F. (1987) Role of the fat body in the regulation of host-seeking behaviour in the mosquito, Aedes aegypti. J. Insect Physiol. 33, 643–646.Google Scholar
Lacher, V. (1967) Elektrophysiologische Untersuchungen an einzelnen Geruchrezeptoren auf den Antennen weiblicher Moskitos (Aedes aegypti L.) J. Insect Physiol. 13, 1461–1470.Google Scholar
Mayer, M. S. and James, J. D. (1969) Attraction of Aedes aegypti (L.): responses to human arms, carbon dioxide, and air currents in a new type of olfactometer. Bull. Ent. Res. 58, 629–642.Google Scholar
Mclver, S. B. (1974) Fine structure of antennal grooved-pegs of the mosquito, Aedes aegypti. Cell Tissue Res. 153, 327–337.Google Scholar
Mukwaya, L. G. (1976) The role of olfaction in host preference by Aedes simpsoni and Aedes aegypti. Physiol. Ent. 1, 271–276.CrossRefGoogle Scholar
Smith, C. N., Smith, N., Gouck, H. K., Weidhaus, D. E., Gilbert, I. H., Mayer, M. S., Smittle, B. J. and Hofbauer, A. (1970) L-lactic acid as a factor in the attraction of Aedes aegypti to human hosts. Ann. Ent. Soc. Am. 63, 760–770.Google Scholar