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Use of A Clinical Data Registry to Evaluate Medical Technologies: Experience from the International Bone Marrow Transplant Registry

Published online by Cambridge University Press:  10 March 2009

Alfred A. Rimm ,
Judith T. Barr ,
Mary M. Horowitz  and
Mortimer M. Bortin
Alfred A. Rimm
Affiliation:
Medical College of Wisconsin
Judith T. Barr
Affiliation:
Harvard School of Public Health
Mary M. Horowitz
Affiliation:
Medical College of Wisconsin
Mortimer M. Bortin
Affiliation:
Medical College of Wisconsin
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Abstract

We reviewed the 18 disease-specific evaluations that used the data base of the International Bone Marrow Transplant Registry to determine the effectiveness of alternative strategies for bone marrow transplant. We identify 17 treatment variables that physicians can control and report the associations between these variables and five clinical endpoints: stable engraftment, graft-versus-host disease, development of interstitial pneumonia, relapse, and disease-free survival. We also suggest policies to promote active participation in establishing and operating a registry.

Type
Special Section: The Contribution Of Medical Registries To Technology Assessment
Information
International Journal of Technology Assessment in Health Care , Volume 7 , Issue 2 , Spring 1991 , pp. 182 - 193
Copyright
Copyright © Cambridge University Press 1991

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