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OPTIMIZATION OF PERIPHERAL BLOOD STEM CELL COLLECTION BY LEUKOPHERESIS

Interaction between Economic and Clinical Assessment of an Innovation

Published online by Cambridge University Press:  01 January 1999

Anne-Gaëlle Le Corroller
Affiliation:
I.N.S.E.R.M. and Paris II University
Jean-Paul Moatti
Affiliation:
I.N.S.E.R.M. and Méditerranée University
Christian Chabannon
Affiliation:
Institut Paoli-Calmettes
Catherine Faucher
Affiliation:
Institut Paoli-Calmettes
Cécile Fortanier
Affiliation:
I.N.S.E.R.M. and Méditerranée University
Patrick Ladaique
Affiliation:
Institut Paoli-Calmettes
Jean-Louis Blache
Affiliation:
Institut Paoli-Calmettes
Gisèle Novakovitch
Affiliation:
Institut Paoli-Calmettes
Dominique Maraninchi
Affiliation:
Institut Paoli-Calmettes
Didier Blaise
Affiliation:
Institut Paoli-Calmettes

Abstract

Using the example of substitution of peripheral blood stem cell (PBSC) collection to bone marrow harvest for autologous transplantation in cancer patients, our study attempts to illustrate how economic assessment, starting at an early stage of medical innovation, can influence the development and diffusion process of a new technological procedure whose optimal design has not yet been established. Two cost minimization studies comparing costs for obtaining a clinically reinfusable graft using bone marrow harvest or alternatively various protocols of PBSC collection contributed to a change in the French clinical standard for this procedure.

Type
GENERAL ESSAYS
Copyright
© 1999 Cambridge University Press

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